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S.-Y. Yu, E.-S. Kim, H.-W. Kwak; Fundus Autofluorescence in Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2609.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate fundus autofluorescence (FAF) patterns in central serous chorioretinopathy (CSC) and correlate it with the finding of optical coherence tomography (OCT), fluorescenin angiography (FA) and indocyanine green angiography (ICGA) and to evaluate FAF changes following verteporfin photodynamic therapy (PDT) for chronic CSC.
Thirty three eyes of 31 patients diagnosed with CSC were examined. The FAF images were obtained using a scanning laser ophthalmoscope (HRA2, Heidelberg Engineering, Germany), and compared with OCT, FA and ICGA finding. Verteporfin PDT was performed using the recommended standard procedure and laser spots were applied to the areas of choroidal vascular hyperpermeability.
In typical acute CSC, eyes showed mild decrease or minimal change of FAF, and in some multiple pinpoints of increased FAF in area of the neurosensory retinal detachment. In various chronic CSC, focal area of increased FAF (in area area of PED), focal reticular pattern, multiple irregular pattern, and diffused changes of RPE tract were recorded. Following PDT, multiple pinpoints and plaque-like increased FAF were detected and then disappeared.
The different FAF were recorded according to the activity of disease and status of the RPE. The changes of FAF after PDT were disappeared. FAF imaging may provide useful information additional to that obtained by FA and ICGA.
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