Purpose:
To describe the ability of the Optos P200MA prototype ultra-widefield fluorescein angiography system to evaluate patients with retinovascular disease. The widefield imaging system (200 degree retinal view) incorporates a red-green scanning laser for acquisition of "color" fundus images and a blue (488 nm) scanning laser for acquisition of fundus fluorescein angiographic images.
Methods:
Single-center, retrospective, non-comparative, case-series.
Results:
One normal volunteer and 5 patients with retinovascular disease were successfully imaged with the Optos P200MA ultrawidefield fluorescein angiographic system. Diseases evaluated with prototype ultra-widefield system included: proliferative diabetic retinopathy (PDR), central retinal vein occlusion, branch/hemi retinal vein occlusion, proliferative sickle-cell retinopathy, and myopic macular degeneration with choroidal neovascularization. In addition to providing high resolution (13 microns) angiographic images of the retinal periphery showing wide-spread capillary non-perfusion in 2 patients (1 patient with proliferative sickle-cell retinopathy seen in the image below and 1 patient with PDR), the P200MA system also provided good resolution angiographic images of the macula in the normal volunteer as well as the patient with myopic choroidal neovasculization.
Conclusions:
Our clinical experience with the Optos P200MA with fluorescein capability demonstrates that it appears to be a viable system for simultaneous angiographic imaging of the posterior pole and retinal periphery in patients with a variety of retinal vascular diseases. It appears to be particularly helpful in delineating areas of peripheral retinal non-perfusion and peripheral foci of neovascularization. Future comparative studies are planned to compare the Optos P200MA versus conventional fluorescein angiogrpahy in evaluting peripheral retinal pathology.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • vascular occlusion/vascular occlusive disease • retina