May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Utility of Optos P200MA for Simultaneous Fluorescein Angiographic Imaging of the Posterior Pole and Retinal Periphery in Patients With Retinovascular Disease
Author Affiliations & Notes
  • A. A. Moshfeghi
    Ophthalmology, Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine, Palm Beach Gardens, Florida
  • C. A. Puliafito
    Ophthalmology, Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine, Miami, Florida
  • Footnotes
    Commercial Relationships A.A. Moshfeghi, Optos, Inc., R; C.A. Puliafito, Optos, Inc., C.
  • Footnotes
    Support Supported by an NIH Center Grant P30 EY014801 and unrestricted grant to the University of Miami from Research to Prevent Blindness.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2611. doi:
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    • Get Citation

      A. A. Moshfeghi, C. A. Puliafito; Utility of Optos P200MA for Simultaneous Fluorescein Angiographic Imaging of the Posterior Pole and Retinal Periphery in Patients With Retinovascular Disease. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2611.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To describe the ability of the Optos P200MA prototype ultra-widefield fluorescein angiography system to evaluate patients with retinovascular disease. The widefield imaging system (200 degree retinal view) incorporates a red-green scanning laser for acquisition of "color" fundus images and a blue (488 nm) scanning laser for acquisition of fundus fluorescein angiographic images.

 
Methods:
 

Single-center, retrospective, non-comparative, case-series.

 
Results:
 

One normal volunteer and 5 patients with retinovascular disease were successfully imaged with the Optos P200MA ultrawidefield fluorescein angiographic system. Diseases evaluated with prototype ultra-widefield system included: proliferative diabetic retinopathy (PDR), central retinal vein occlusion, branch/hemi retinal vein occlusion, proliferative sickle-cell retinopathy, and myopic macular degeneration with choroidal neovascularization. In addition to providing high resolution (13 microns) angiographic images of the retinal periphery showing wide-spread capillary non-perfusion in 2 patients (1 patient with proliferative sickle-cell retinopathy seen in the image below and 1 patient with PDR), the P200MA system also provided good resolution angiographic images of the macula in the normal volunteer as well as the patient with myopic choroidal neovasculization.

 
Conclusions:
 

Our clinical experience with the Optos P200MA with fluorescein capability demonstrates that it appears to be a viable system for simultaneous angiographic imaging of the posterior pole and retinal periphery in patients with a variety of retinal vascular diseases. It appears to be particularly helpful in delineating areas of peripheral retinal non-perfusion and peripheral foci of neovascularization. Future comparative studies are planned to compare the Optos P200MA versus conventional fluorescein angiogrpahy in evaluting peripheral retinal pathology.  

 
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • vascular occlusion/vascular occlusive disease • retina 
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