Abstract
Purpose::
To compare OCT images obtained on the Zeiss Stratus OCT (Carl Zeiss Meditec, Inc and the Topcon 3D-OCT device (Topcon Corp., Tokyo Japan).
Methods::
The Topcon 3D-OCT Fourier domain optical coherence tomography machine records the interferometric information using a spectrometer approach instead of moving mirrors used in conventional OCT systems, allowing for an increase in the scanning speed (25,000 A-scan/sec). Through an integration with the Topcon non-mydratic retinal camera, the Topcon 3D-OCT provides high resolution cross sectional (B-scan) and three-dimensional volumetric images of the posterior fundus.The system utilizes a near-infrared, low coherence Superluminiscent Diode (830nm) light source, achieving excellent axial (6 um) and lateral (10 um) resolution. In the cross-sectional (2D) imaging mode, a densely-sampled OCT image (4096 A-scans) can be obtained <0.3 seconds, reducing potential eye movement artifact.In this study, 20 eyes of patients with retinal disease were imaged with the Topcon 3D-OCT using cross sectional scans. The authors reviewed the images with respect to their subjective and objective quality. Comparable scans were also obtained with Stratus OCT (Carl Zeiss Meditec, Inc).
Results::
Paired images obtained by both the Topcon 3D-OCT and the Stratus OCT from either or both eyes of each subject were masked and evaluated by readers who independently assessed the diagnostic information contained in each image using standardized image evaluation forms. Using the Sign Test for Paired Data, scores for paired images were examined to test the hypothesis that the median difference between the matched images is not significant (i.e., not clinically meaningful). Images between the two devices were found to be equivalent in terms of producing images of adequate diagnostic information.
Conclusions::
The Topcon 3D-OCT provided useful OCT imaging of retinal diseases when compared to the same patient images taken on the Zeiss Stratus OCT. The images of these patients were compared on both instruments and found to be of similar diagnostic value. Further clinical studies are planned.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina • age-related macular degeneration