May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Optical Coherence Tomography: Comparison of Artefacts Produced by Fast Macular Thickness Map and by Macular Thickness Map
Author Affiliations & Notes
  • M. Cereda
    University of Milan, Milano, Italy
    Department of Oftalmology Sacco Hospital Milano,
  • A. Giani
    University of Milan, Milano, Italy
    Department of Oftalmology Sacco Hospital Milano,
  • L. Fonte
    University of Milan, Milano, Italy
    Sacco Hospital Milano,
  • A. Invernizzi
    University of Milan, Milano, Italy
    Department of Oftalmology Sacco Hospital Milano,
  • M. Pellegrini
    University of Milan, Milano, Italy
    Department of Oftalmology Sacco Hospital Milano,
  • G. Staurenghi
    University of Milan, Milano, Italy
    Department of Oftalmology Sacco Hospital Milano,
  • Footnotes
    Commercial Relationships M. Cereda, None; A. Giani, None; L. Fonte, None; A. Invernizzi, None; M. Pellegrini, None; G. Staurenghi, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 2622. doi:
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      M. Cereda, A. Giani, L. Fonte, A. Invernizzi, M. Pellegrini, G. Staurenghi; Optical Coherence Tomography: Comparison of Artefacts Produced by Fast Macular Thickness Map and by Macular Thickness Map. Invest. Ophthalmol. Vis. Sci. 2007;48(13):2622.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To evaluate differences in number and gravity of artefacts produced by two scan protocols using Stratus OCT:Fast Macular Thickness Map and Macular Thickness Map.

Methods:: A prospective,observational case series study was developed in order to investigate the topic.A population of 43 outpatients was enrolled.Every patient underwent Stratus OCT examination(Carl Zeiss Meditech,Dublin,California)using both FMTM and MTM.Only one eye of each patient was used randomizing with a coin.With these scan modes, six radial scans were obtained.Each radial scan was manually analyzed by expert operators in order to determine the presence of artefacts in detection of inner and outer limit of retina, using Retinal Thickness (single eye) analysis method.A score of gravity was given considering distance from the fovea (1=located in the outer ring area of the map,from 3 to 4.5 mm to the centre;2=located in the middle ring area,from 1.5 to 3 mm to the centre;3=located in the inner ring area,3 mm of diameter).Conditional logistic regression,adjusted for clustering according to individuals,was used to evaluate a discordance in the probability of having artefacts of the two methods.To evaluate seriousness of the artefacts simple regression was used.

Results:: 43 eyes were enrolled in the study.Mean age was 66.9±1.6.The odds ratio of having an artefact using the fast method compared to the normal method is 1.83 (p=0.06; CI: 0.97-3.46).No relation has been shown according to the gravity of the artefacts.

Conclusions:: According to the results no differences have been shown beetwen the two methods.Anyway other studies are necessary to better evaluate errors produced by OCT analysis on retinal thickness measurement. In particular,it would be interesting to investigate if the number of artefacts could change in different pathologies affecting retina.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina • clinical (human) or epidemiologic studies: systems/equipment/techniques 
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