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T. G. Zeyen, I. Stalmans, E. Vandewalle, EGPS Study Group; Agreement Between Non-Expert Ophthalmologists in the Assessment for Glaucomatous Change in Serial Optic Disc Stereo Photos Before and After a Training Session. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3340.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the agreement in the assessment for glaucomatous change in serial optic disc stereo photos between experts and non-experts and to re-evaluate the agreement between non-experts after a training session.
Three experts (senior readers for the European Glaucoma Prevention Study) evaluated for change a set of two serial optic disc color stereo-slides of 40 patients, masked from the temporal sequence of the slides (Ophthalmology 2003;110:340-4). Thirty seven (37) non-expert ophthalmologists independently evaluated twice the same set of optic disc stereo slides. The second evaluation was masked from the previous evaluation and took place the same day after a training session on a separate slide set. Kappa statistics were used to evaluate the inter-observer agreement. A Mann-Whitney U test was used to compare the kappa coefficients between experts and non-experts. A Wilcoxon signed-rank test was used to compare the kappa coefficients of the non-experts before and after the training session.
The mean inter-observer kappa coefficient of the experts and non-experts was 0.55 (95% CI: 0.47-0.63) and 0.33 (95% CI: 0.27-0.40), respectively (Mann-Whitney U test, p=0.014). After a training session, the mean kappa coefficient of the non-experts increased to 0.38 (95% CI: 0.32-0.43) (signed rank test, p=0.068).
The agreement between non-expert ophthalmologists in assessing serial optic disc stereo photos was poor but improved to almost fair after a training session.
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