May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Macular Pseudoholes in Retinitis Pigmentosa
Author Affiliations & Notes
  • A. R. Gaudio
    Berman-Gund Laboratory for the Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
  • E. L. Berson
    Berman-Gund Laboratory for the Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
  • M. A. Sandberg
    Berman-Gund Laboratory for the Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
  • Footnotes
    Commercial Relationships A.R. Gaudio, None; E.L. Berson, None; M.A. Sandberg, None.
  • Footnotes
    Support NIH Grant EY00169 and The Foundation Fighting Blindness, Owings Mills, MD
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3726. doi:
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    • Get Citation

      A. R. Gaudio, E. L. Berson, M. A. Sandberg; Macular Pseudoholes in Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3726.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To estimate the prevalence and effect on visual acuity of macular pseudoholes and lamellar macular holes in patients with retinitis pigmentosa.

Methods:: We studied 316 patients with typical forms of retinitis pigmentosa, evaluating their macular appearance by ophthalmoscopy, fundus photography and optical coherence tomography (OCT 3).

Results:: Eleven patients (3%) with an average age of 41 years were found to have macular pseudoholes or lamellar holes in one or both eyes. Their visual acuities ranged from 20/20 to 20/60 with the average reduction being 2 lines. The ocular media were clear. No patient in this series was found to have a full thickness macular hole.

Conclusions:: Macular pseudoholes and lamellar holes occur at a higher frequency in retinitis pigmentosa than in the general population. In retinitis pigmentosa they have a slight to moderate effect on visual acuity.

Keywords: retinal degenerations: hereditary • clinical (human) or epidemiologic studies: prevalence/incidence • macular holes 
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