Abstract
Purpose::
Aim of the study was to examine whether patients with migraine without aura have acquired colour vision disturbances.
Methods::
The ophthalmological examination includes morphological status, visual acuity, refraction, intraocular pressure, and the cup/disk-ratio. Colour vision was examined with the Ishihara colour plates and with the HMC anomaloscope (Oculus, Germany).
Results::
Thirtytwo patients (m:f=2:30) with two subgroups (group 1: n=14, mean age 30+7.25 years, duration of migraine: 9.92±5.8 years; group 2: n=18, mean age 48.5+6 years, duration of migraine: 24.94±9.95 years;) and 32 generally healthy controls (m:f=10:12; controls 1: n=14, mean age 29.93±6.89 years; controls 2: n=18, mean age 49.28±5.98 years) were examined. Visual acuity, refraction, intraocular pressure and the cup/disk-ratio of the patients as well as the readings with the Ishihara plates were within normal ranges. A statistically significant difference was found in the absolute and relative Rayleigh matches (absolute Rayleigh match: group 1 versus controls 1: p<0.001, group 2 versus controls 2: p=0.009; relative Rayleigh matches: group 1 versus controls 1: p=0.003, group 2 versus controls 2: not significantly different).
Conclusions::
Although patients with migraine without aura appeared ophthalmologically healthy under routine eye examination, colour vision was disturbed in the red-green axis. This should be considered in anomaloscope examinations.