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C. Erb, M. Boyraz, A. Schröder; Anomaloscope Matches in Patients With Migraine Without Aura. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3810.
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Aim of the study was to examine whether patients with migraine without aura have acquired colour vision disturbances.
The ophthalmological examination includes morphological status, visual acuity, refraction, intraocular pressure, and the cup/disk-ratio. Colour vision was examined with the Ishihara colour plates and with the HMC anomaloscope (Oculus, Germany).
Thirtytwo patients (m:f=2:30) with two subgroups (group 1: n=14, mean age 30+7.25 years, duration of migraine: 9.92±5.8 years; group 2: n=18, mean age 48.5+6 years, duration of migraine: 24.94±9.95 years;) and 32 generally healthy controls (m:f=10:12; controls 1: n=14, mean age 29.93±6.89 years; controls 2: n=18, mean age 49.28±5.98 years) were examined. Visual acuity, refraction, intraocular pressure and the cup/disk-ratio of the patients as well as the readings with the Ishihara plates were within normal ranges. A statistically significant difference was found in the absolute and relative Rayleigh matches (absolute Rayleigh match: group 1 versus controls 1: p<0.001, group 2 versus controls 2: p=0.009; relative Rayleigh matches: group 1 versus controls 1: p=0.003, group 2 versus controls 2: not significantly different).
Although patients with migraine without aura appeared ophthalmologically healthy under routine eye examination, colour vision was disturbed in the red-green axis. This should be considered in anomaloscope examinations.
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