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A. Katsanos, G. Labiris, M. Pefkianaki, T. Tsirouki, M. Fanariotis, D. Chatzoulis; Rarebit Perimetry: Correlation With OCT Measurements. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3840.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate correlations between Rarebit microdot perimetry scores and OCT-derived RNFL thickness measurements.
One randomly selected eye of 32 consecutive white POAG patients without significant cataract (age: 61.7 ± 11.7 years, MD: -3.05 ± 4.95 dB) and 16 healthy white individuals (age: 33.75 ± 6.2 years, MD: -0.77 ± 0.81 dB) was included in the study. Participants were examined with Rarebit perimetry (central field test, software version 4) and Stratus OCT (fast RNFL). The tests were performed within two months from each other. Correlation was investigated between superior (S), inferior (I) and global Rarebit and OCT RNFL parameters.
After Bonferroni correction, for the relationship between global Rarebit scores and OCT parameters for the glaucoma patients, significant correlation was found between Mean Hit Rate (MHR) and Max-Min (r=0.470, p=0.014), Hit Rate<90 and Max-Min (r=-0.413, p=0.038), Average Hit Rate<90 and Max-Min (r=0.482, p=0.01) and Average Hit Rate<90 and Average Thickness (r=0.439, p=0.024). Regarding the relationship between superior and inferior OCT parameters and the corresponding Rarebit scores, no significant correlation was found within the glaucoma subgroup. However, % Miss Rate-I had a significant correlation with Max-Min (r=-0.510, p=0.006) whereas % Miss Rate-S tended to have a significant correlation with Max-Min (r=-0.393, p=0.052). Within the control subgroup no significant correlations were found.
Our results indicate that general measures of integrity of the retinal neural matrix as measured with Rarebit perimetry seem to correlate with OCT-derived RNFL thickness values.
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