May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Anterior Segment Optical Coherence Tomography for Imaging the Change in Anterior Chamber Angle Morphology After Cataract Surgery
Author Affiliations & Notes
  • F. Memarzadeh
    Ophthalmology, Univ of Southern California, Doheny Eye Institutue, Los Angeles, California
  • M. Tang
    Ophthalmology, Univ of Southern California, Doheny Eye Institutue, Los Angeles, California
  • Y. Li
    Ophthalmology, Univ of Southern California, Doheny Eye Institutue, Los Angeles, California
  • V. Chopra
    Ophthalmology, Univ of Southern California, Doheny Eye Institutue, Los Angeles, California
  • B. A. Francis
    Ophthalmology, Univ of Southern California, Doheny Eye Institutue, Los Angeles, California
  • D. Huang
    Ophthalmology, Univ of Southern California, Doheny Eye Institutue, Los Angeles, California
  • Footnotes
    Commercial Relationships F. Memarzadeh, None; M. Tang, Carl Zeiss Meditec, Inc., F; Y. Li, Carl Zeiss Meditec, Inc, F; V. Chopra, None; B.A. Francis, None; D. Huang, Carl Zeiss Meditec, Inc, P.
  • Footnotes
    Support NIH R24 EY 13015 grant from National Eye Institute, Bethesda, MD. Research equipment and grant from Carl Zeiss Meditec, Inc., Dublin, CA.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3855. doi:
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    • Get Citation

      F. Memarzadeh, M. Tang, Y. Li, V. Chopra, B. A. Francis, D. Huang; Anterior Segment Optical Coherence Tomography for Imaging the Change in Anterior Chamber Angle Morphology After Cataract Surgery. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3855.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To evaluate and quantify changes in the anterior chamber morphologyafter small incision cataract extraction and intraocular lens(IOL) placement using anterior segment optical coherence tomography(ASOCT)

 
Design:
 

Prospective comparative observational case series.

 
Methods:
 

We examined the anterior chamber configuration of 32 eyes of32 patients before and after small incision cataract extractionand posterior chamber IOL implantation by means of ASOCT. Centralanterior chamber depth (ACD) was measured, along with severalangle parameters: angle opening distance at 500 µm fromscleral spur (AOD 500) and trabecular-iris space at 500 µmand 750 µm (TISA 500 and 750). Pre-operatively lens thickness(LT) and lens position (LP) defined as ACD + ½ LT were calculated

 
Results:
 

Preoperative ACD and LT were highly correlated (r = -0.46, P= 0.0083) as were ACD and TISA 500 (r = 0.63, P = 0.0001). LPwas highly correlated with TISA 500 (r=0.52, P=0.0001). However,LT did not correlate with TISA 500 (r = -0.11, P= 0.74). Themean ACD, AOD 500, TISA 500 and TISA 750 all increased significantlyafter cataract extraction (p<0.001), Table, Figure. The degreeof angle widening was not correlated with preoperative angleor lens parameters.

 
Conclusions:
 

Preoperative lens thickness affects central anterior chamberdepth, but does not seem to significantly affect angle opening.The position of the lens may have a greater influence on anglewidth. Regardless of preoperative anatomy, cataract extractionsignificantly deepens the anterior chamber and widens the angle.These changes can be objectively quantified by anterior segmentOCT. 

 

 
Keywords: anterior segment • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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