May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Prevalence of Plateau Iris Configuration and Morphometric Findings in Patients With Narrow Angle or Primary Angle-Closure Glaucoma on Ultrasound Biomicroscopic Examinations
Author Affiliations & Notes
  • S. Cronemberger
    Ophthalmology, Federal Univ of Minas Gerais, Belo Horizonte, Brazil
  • A. Diniz Filho
    Ophthalmology, Federal Univ of Minas Gerais, Belo Horizonte, Brazil
  • D. Martins Ferreira
    Ophthalmology, Federal Univ of Minas Gerais, Belo Horizonte, Brazil
  • N. Calixto
    Ophthalmology, Federal Univ of Minas Gerais, Belo Horizonte, Brazil
  • Footnotes
    Commercial Relationships S. Cronemberger, None; A. Diniz Filho, None; D. Martins Ferreira, None; N. Calixto, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3863. doi:
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      S. Cronemberger, A. Diniz Filho, D. Martins Ferreira, N. Calixto; Prevalence of Plateau Iris Configuration and Morphometric Findings in Patients With Narrow Angle or Primary Angle-Closure Glaucoma on Ultrasound Biomicroscopic Examinations. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3863.

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Abstract

Purpose:: To present the prevalence and morphometric findings of plateau iris (PI) configuration on eyes of glaucomatous patients with narrow-angle or primary angle-closure glaucoma submitted to UBM examination.

Methods:: Retrospective study analyzing the UBM images of 228 patients from September 1995 to August 2006. The inclusion criteria for PI configuration was the complete (complete plateau) or almost complete (incomplete plateau) absence of ciliary sulcus on UBM examination. The antiglaucomatous medications were withdraw 48 hours before the UBM exam. We excluded the blind eyes from patients with primary angle-closure glaucoma and the eyes that underwent an intraocular surgery. In all eyes with PI we assessed: the central corneal thickness (CCT); the central anterior chamber depth (CACD); the angle opening distance at 500 µm of the scleral spur (AOD500); the peripheral iris thickness (IT) at 500 µm of the scleral spur; the iris-ciliary process distance (ICPD); the trabecular-ciliary process distance (TCPD) and the area of recess of the angle (ARA) taken in the temporal quadrant. We used the UBM Pro 2000 software for the measurements and the SPSS 13.0 for the statistical analysis.

Results:: One hundred and seventy one (75%) out of 228 patients were female and 57 (25%) were male. Twenty two patients (37 eyes) had PI corresponding to the prevalence of 9.6%. Six eyes were excluded because of blindness and one eye because underwent a penetrating keratoplasty. Twenty three (62.2%) eyes of 15 patients had complete PI and 14 eyes from 7 patients (37.8%), had incomplete PI. Two patients (9.1%) had PI syndrome in both eyes. Seventeen (77.3%) out of 22 patients with PI were female and 5 (22.7%) were male. No statistical significant difference was found between the morphometric findings of the eyes with complete and incomplete PI except for the ICPD. However, when we made the comparison between them and those of normal eyes, we found that all parameters of the eyes with PI showed lower values, being the statistic differences highly significant with the exception of CCT and IT.

Conclusions:: The prevalence of PI was of 9.6%, being much higher in females (77.3%) with a difference statistically significant. No difference statistically significant was found between the morphometric findings of complete and incomplete PI, except for ICPD. However, all the measures of the eyes with PI showed lower values when compared to those of normal eyes, being the statistic differences highly significant with the exception of CCT and IT.

Keywords: clinical (human) or epidemiologic studies: prevalence/incidence • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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