May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Epi-Lasik : A Confocal Microscopy Analysis of the Corneal Epithelium and Anterior Stroma
Author Affiliations & Notes
  • M. Ramirez
    Cornea, Asoc para Evitar la Ceguera, Mexico City, Mexico
  • E. Hernandez-Quintela
    Cornea, Asoc para Evitar la Ceguera, Mexico City, Mexico
  • F. Beltran
    Cornea, Asoc para Evitar la Ceguera, Mexico City, Mexico
  • R. Naranjo-Tackman
    Cornea, Asoc para Evitar la Ceguera, Mexico City, Mexico
  • Footnotes
    Commercial Relationships M. Ramirez, None; E. Hernandez-Quintela, None; F. Beltran, None; R. Naranjo-Tackman, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3878. doi:https://doi.org/
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      M. Ramirez, E. Hernandez-Quintela, F. Beltran, R. Naranjo-Tackman; Epi-Lasik : A Confocal Microscopy Analysis of the Corneal Epithelium and Anterior Stroma. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3878. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To evaluate the confocal microscopy findings at the corneal epithelium and the anterior stroma after epi-LASIK Surgery.

Methods:: 10 eyes from 10 patients underwent epi-LASK, epithelial flaps were created with the Amadeus II, epi-LASIK-LASIK microkeratome (Ziemer ophthalmics systems AG, Switzerland). A Visx star 4 system (Visx, Santa Ana, CA, USA) was used to perform the myopic and/or astigmatic laser ablation in all eyes. A central scan of the total corneal thickness was taken with the confocal microscope (Confoscan 4, Fortune Technologies, Italy) before, at 2 weeks and 1 month after surgery. Corneal epithelial thickness and keratocytes morphology at the anterior stroma were analyzed by using the NAVIS software V. 3.5.0 (NIDEK, Multi-Instrument Diagnostic System, Japan).

Results:: Mean epithelial thickness was 44 ± 2.8 µm before surgery. At 2 week after surgery, epithelial thickness decrees 18% (36.5 ± 3.9 µm P < 0.05). At 1 month after surgery epithelial thickness persist 20% thinner than the pre-epi-LASIK measurement (35.4 ± 5.6 µm P < 0.05). The anterior corneal stroma showed more keratocyte activation at 1 month than 2 week after Surgery.

Conclusions:: Corneal epithelium thickness decrees at 2 weeks after epi-LASIK and persist at 1 month after surgery. The anterior stroma showed more keratocyte activation at 1 month than 2 week after Surgery.

Keywords: refractive surgery: other technologies • cornea: epithelium • cornea: stroma and keratocytes 
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