May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Epidemiology and Etiology of Uveitis in a Referral Center in Mexico City
Author Affiliations & Notes
  • A. E. Polifroni Lobo, Sr.
    Uveitis e Inmunologia Ocular, Instituto de Oftalmologia Fundacion Conde de Valenciana, Distrito Federal, Mexico
  • S. Voorduin, V
    Uveitis e Inmunologia Ocular, Instituto de Oftalmologia Fundacion Conde de Valenciana, Distrito Federal, Mexico
  • M. Pedroza, V
    Uveitis e Inmunologia Ocular, Instituto de Oftalmologia Fundacion Conde de Valenciana, Distrito Federal, Mexico
  • Footnotes
    Commercial Relationships A.E. Polifroni Lobo, None; S. Voorduin, None; M. Pedroza, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3886. doi:
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      A. E. Polifroni Lobo, Sr., S. Voorduin, V, M. Pedroza, V; Epidemiology and Etiology of Uveitis in a Referral Center in Mexico City. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3886.

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Abstract

Purpose:: To determine the epidemiology and etiology of the uveitis in our referral center in Mexico City following the International Consense new guidelines for standardization of the uveitis nomenclature (SUN Working Group).

Methods:: We did a prospective and descriptive study of 102 patients (174 eyes) with uveitis in the Instituto de Oftalmología, Conde de Valenciana in Mexico City between February and November 2006. We evaluated epidemiologic indicators, social history, evolution time of the disease, clinical presentation, time duration, curse, disease activity, anatomic, etiologic and pathologic diagnosis.

Results:: 58% of patients were female, the medium age was 38.1 years (SD+ 18.31). The mean follow-up time was 5.21 months (range 1-9.3 months). The mean evolution time of the disease was 176.9 days (SD +258). 50% of the uveitis had an abrupt onset, 57% were persistent and 54% had an acute course. The most frequent anatomic diagnosis was anterior uveitis (47.1%), followed by panuveitis (25.5%), posterior uveitis (17.6%), and intermediate (10.8%). Most of the cases were of idiopathic etiology (55.8%), followed by herpes simplex (8.8%), toxoplasmosis (7.8%), Vogt-Koyanagi-Harada (3.9%), toxocariasis (3.9%), ocular syphilis (2.9%), chronic postsurgical uveitis (2.9%) and rheumatoid arthritis (2%). 25.4% were infectious uveitis and 69.7% had a non-granulomatous inflammation. La commonest complications were: vitreous opacities (31.4%), cataract (22.5%), cystoid macular edema (12.7%), retinal detachment (8.8%), corneal leucoma (8.8%) and glaucoma (6.9%). At the end of the follow-up, 28.4% were legally blind.

Conclusions:: In our study, the uveitis had an idiopathic, acute and persistent, non-granulomatous and non-infectious behavior. The most common anatomic site was anterior uveitis.

Keywords: uvea • clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology • clinical (human) or epidemiologic studies: prevalence/incidence 
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