May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Psychophysical and Electrophysiologic Findings in Vogt-Koyanagi-Harada Syndrome
Author Affiliations & Notes
  • A. I. Perez, III
    Fundación Hospital Nuestra Señora de la Luz, I.A.P., México, D.F., Mexico
  • R. García
    Fundación Hospital Nuestra Señora de la Luz, I.A.P., México, D.F., Mexico
  • T. Valdez
    Fundación Hospital Nuestra Señora de la Luz, I.A.P., México, D.F., Mexico
  • F. Martínez
    Fundación Hospital Nuestra Señora de la Luz, I.A.P., México, D.F., Mexico
  • J. Rojas
    Fundación Hospital Nuestra Señora de la Luz, I.A.P., México, D.F., Mexico
  • E. López
    Fundación Hospital Nuestra Señora de la Luz, I.A.P., México, D.F., Mexico
  • Footnotes
    Commercial Relationships A.I. Perez, None; R. García, None; T. Valdez, None; F. Martínez, None; J. Rojas, None; E. López, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3902. doi:
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    • Get Citation

      A. I. Perez, III, R. García, T. Valdez, F. Martínez, J. Rojas, E. López; Psychophysical and Electrophysiologic Findings in Vogt-Koyanagi-Harada Syndrome. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3902.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To describe findings in psychophysical and electrophysiologic tests, in adults with Vogt Koyanagi Harada Syndrome, convalescent phase, with good visual capacity (≥ 20/40), without complications associated.

Methods:: Prospective, descriptive, cross-sectional and observational study. We made three psychophysical tests (color sensitivity, contrast sensitivity, and dark adaptation) and two electrophysiologic tests (electroretinogram and electro-oculogram). In all tests Optoelectronic Stimulator of the system VISION MONITOR® (METROVISION®) was used, except for color sensitivity that was determined by means of Farnsworth D-15 and cards of Ishihara tests.

Results:: We included 11 patients, 10 female and 1 male (18 eyes), with age average of 38.1 years. The time of diagnosis of the illness varied between 2 and 72 months (average = 25.2 ±22.1) and the time of inactivity when we making the tests was 14.1 (±22.5) months. The patients had presented in average 1.4 (±0.8) episodes of activity. 16.7% of the eyes were abnormal in color sensitivity, without a characteristic axis. In contrast sensitivity the tendency was to present greater alteration in high space frequencies (100% of the cases) and in smaller degree towards the medium (72.2%) and low frequencies (38.8%). Bad adaptation to the dark in the cones in 5.5% of the eyes and the rods in the 27.7% existed. Electro-oculogram was normal in most of the cases (average=258 ±94.7). The phases of the electroretinogram more affected were the mesopic, oscillatory potentials and flicker macular. Itself not relation of the results found in our subjects of study with the time of beginning and inactivity of the illness and number of active events was observed.

Conclusions:: The Via-Rods and the Via-Central Cones were the most affected in our group of study, not the EPR. The Vogt Koyanagi Harada Syndrome could leave permanent sequels in the retinal function, compatible with good visual capacity but not with good visual quality.

Keywords: uvea • chorioretinitis • electrophysiology: clinical 
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