May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Effect of Second SLT on IOP
T. C. Franco; R. Calvo; A. Kawayeh; C. Marcus; A. Prywes; R. Rothman; J. Weinstein; J. B. Serle
Author Affiliations & Notes
  • T. C. Franco
    Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York
  • R. Calvo
    Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York
  • A. Kawayeh
    Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York
  • C. Marcus
    Glaucoma Consultants of Long Island, Lake Success, New York
  • A. Prywes
    Glaucoma Consultants of Long Island, Lake Success, New York
  • R. Rothman
    Glaucoma Consultants of Long Island, Lake Success, New York
  • J. Weinstein
    Glaucoma Consultants of Long Island, Lake Success, New York
  • J. B. Serle
    Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York
    Glaucoma Consultants of Long Island, Lake Success, New York
  • Footnotes
    Commercial Relationships T.C. Franco, None; R. Calvo, None; A. Kawayeh, None; C. Marcus, None; A. Prywes, None; R. Rothman, None; J. Weinstein, None; J.B. Serle, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 3981. doi:
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      T. C. Franco, R. Calvo, A. Kawayeh, C. Marcus, A. Prywes, R. Rothman, J. Weinstein, J. B. Serle; Effect of Second SLT on IOP. Invest. Ophthalmol. Vis. Sci. 2007;48(13):3981.

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Abstract

Purpose:: To assess efficacy of second Selective Laser Trabeculoplasty (SLT-2) in patients with increased IOP.

Methods:: Retrospective chart review from database of 207 eyes that received SLT between April 2003 and May 2005. 146 eyes of 126 patients who had at least four IOP measurements and six months follow up after first SLT (SLT-1) were included. 38 eyes (26%) (35 patients) underwent SLT-2 (Selecta II Glaucoma Laser System). Treatment parameters (mean±SD): 60±13 spots, over 1800 in 21 eyes (55%), over 2700 in 9 eyes (23%), over 3600 in 8 eyes (21%), energy of 0.91 ± 0.17 mJ per pulse. SLT-2 spots overlapped SLT-1 treatment in 42% of eyes. Two-tailed paired t-test was used for statistical analysis.

Results:: Of the 35 patients 14 (40%) were male, 21 (60%) were female, mean age was 69±10.9 years, diagnoses: POAG: 26/35 (74.3%) PXE: 6/35 (17.1%). Narrow: 1 (2.9%) Secondary Glaucoma: 1 (2.9%) Pigmentary: 1 (2.9%). Three eyes (7.9%) had cataract surgery prior to SLT-1 and one eye had previous peripheral iridotomy. There were two eyes (5.3%) which had previous ALT, one eye underwent combined surgery 5.4 months after SLT-2, the other eye had valve implant 1.2 months after SLT-2. Baseline-1 IOP prior to SLT-1 was 21.3 ± 6.3 mmHg. Interval between SLT-1 and SLT-2 was 11.9 ± 8.8 months. Baseline-2 IOP just prior to SLT-2 was 19.5 ± 5.8 mmHg, a decrease (p=0.06) of 1.8 ± 5.7 mmHg (8.3%) from baseline-1. Final IOP 12.6± 8.5 months after SLT-2 was 17.9 ± 6.9 mmHg, a reduction (p=0.051) of 2.1 ± 4.4 mmHg (7.2%) from baseline-2. From baseline-1 to final IOP (20.6 ± 10.1 months) the total IOP reduction (p=0.002) was 2.7 ± 4.5 mmHg (14.2%). No postoperative complications associated with the procedure were identified. Number of medications 3.0 ± 1.4 remained unchanged (p=0.92) through the last visit 2.8 ± 1.0. Six of the 38 eyes (15.8%) underwent glaucoma surgery 5.7±4.9 months following SLT-2.

Conclusions:: Second SLT is effective in some eyes, significantly (p<0.05) reducing IOP up to an additional 7% following a first SLT, and up to 14% compared to pre-SLT IOP.

Keywords: intraocular pressure • laser 
© 2007, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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