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T. Yamashita, A. Uemura, H. Kita, T. Sakamoto; Long-Term Course of Visual Field Defects After Intravitreous Administration of Indocyanine Green in Macular Hole Surgery. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4108.
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To evaluate the long-term course of visual field defects after intravitreous administration of indocyanine green in macular hole surgery.
Seven eyes of 7 patients with visual field defects after adjunctive use of indocyanine green in macular hole surgery between February 2001 and January 2002 were enrolled. Humphrey static perimetry and best-corrected visual acuity were examined periodically. The main outcome measure was mean deviation (MD) of Humphrey (30-2) SITA-fast program.
All patients were followed up for more than 3 years. Preoperative MD was -3.5±3.1 dB (mean±standard deviation [SD]). Postoperative MD was -13.3±4.9 dB at 1 year, -13.4±4.6 dB at 2 years, -16.2±5.1 dB at 3 years. A statistically significant decrease of mean MD was found between 1 year and 3 years after surgery (p<0.05). Fundus examination of the patients with postoperative decreasing of MD showed a pale optic disc. There was no significant difference in postoperative best-corrected visual acuity at any time.
The visual field defect after the use of indocyanine green in macular hole surgery may keep worsening for several years. Indocyanine green associated visual field defect needs long-term follow-up.
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