May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Triamcinolone-Assisted Pars Plana Vitrectomy for Full Thickness Macular Holes
Author Affiliations & Notes
  • R. Somani
    Ophthalmology, University of Alberta, Edmonton, Alberta, Canada
  • C. J. Rudnisky
    Ophthalmology, University of Alberta, Edmonton, Alberta, Canada
  • M. D. J. Greve
    Ophthalmology, University of Alberta, Edmonton, Alberta, Canada
  • B. J. Hinz
    Ophthalmology, University of Alberta, Edmonton, Alberta, Canada
  • Footnotes
    Commercial Relationships R. Somani, None; C.J. Rudnisky, None; M.D.J. Greve, None; B.J. Hinz, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4117. doi:
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    • Get Citation

      R. Somani, C. J. Rudnisky, M. D. J. Greve, B. J. Hinz; Triamcinolone-Assisted Pars Plana Vitrectomy for Full Thickness Macular Holes. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4117.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To evaluate the efficacy and safety of intravitreal triamcinolone acetonide (TA) assisted peeling of internal limiting membranes (ILM).

Methods:: A retrospective review of 108 patients with full thickness macular holes who under went triamcinolone-assisted pars plana vitrectomy.

Results:: The use of triamcinolone allowed for improved visualization of the posterior hyaloid and internal limiting membrane. There were no intra-operative complications or signs of toxicity. Follow up data was available for 83% of patients. No post-operative endophthalmitis was observed. Anatomical closure of the macular hole was achieved in 96% of cases. Retinal detachment was observed in 5.6%. Intra-ocular pressure was found to be elevated above 22 mmHg in 32 (36%) cases. All cases of elevated intra-ocular pressure were treated with topical or oral agents alone. Average duration of treatment was 30 days. The incidence of cataract extraction was 47%.

Conclusions:: TA-assisted vitrectomy is associated with a high macular hole closure rate. TA-assisted removal of the ILM appears to be safe as no cases of endophthalmitis was observed. While its use may be associated with an increase in post-operative intraocular pressure this effect is temporary and is controlled by short term medical therapy.

Keywords: vitreoretinal surgery • clinical (human) or epidemiologic studies: outcomes/complications 
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