Abstract
Purpose::
To assess the association between simulated binocular visual field (BVF) scores and self-reported vision-related quality of life (QOL).
Methods::
Participants in LALES - a population-based prevalence study of eye disease in Latinos age 40 years and older - underwent interviews and a comprehensive ophthalmic examination including visual field testing using the Humphrey Automated Field Analyzer (SITA Standard 24-2). Mean Deviation (MD) scores from each eye were recorded. Monocular visual field (MVF) test results were then used to calculate three simulated BVF scores (best location, and two probability summation scores) based on published algorithms. QOL was assessed by the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Pearson correlation was used to determine correlation between MVF MD and BVF scores as well as the correlation between visional related QOL scores and BVF scores. Linear regression was used to assess the association between QOL and binocular summation score^2. The model was adjusted for covariates that have previously been shown to impact QOL.
Results::
3312 participants were included in the analyses. The average age of the participants was 55 years and 57% were females. Three binocular VF scores (best location, and two probability summation scores) had a high correlation with VF MD at better seeing eye (r=0.94) and a slightly lower correlation with VF MD in the worse eye (r=0.86). The BVF scores also significantly correlated with vision related QOL subscales and composite scale, correlation coefficient ranged from 0.19 (ocular pain) to 0.39 (composite). The correlation coefficients are similar for all three BVF scores. Linear regression analyses indicated decreased binocular probability summation score ^2 were significantly associated with decreased in QOL score. VF loss as assessed by the binocular probability summation score^2 had the greatest impact on driving difficulty (slope (ß=1.48)), vision-related mental health (ß=1.11), and vision-related dependency (ß=1.10) sub-scale scores.
Conclusions::
The binocular best location, summation^2, and summation^4 had similar correlation with QOL. The simulated BVF provides us a tool to measure vision, which may be used for vision related disability measure.
Keywords: quality of life