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S. Y. Shen, T. Y. Wong, P. Foster, J. L. Loo, S. C. Loon, M. Rosman, N. Ishak, A. Foong, S. M. Saw, T. Aung; The Prevalence of Glaucoma in a Malay Population in Asia: The Singapore Malay Eye Study (SiMES). Invest. Ophthalmol. Vis. Sci. 2007;48(13):4342.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the prevalence and type of glaucoma in an urban Malay population.
A population-based, cross-sectional study of Malays aged 40-80 years residing in Singapore. An age-stratified random sampling procedure selected 5,600 Malay names residing in south-western Singapore from the national database. Selected individuals were contacted by telephone and home visits to determine study eligibility. Eligible individuals were invited to a centralized clinic for a standardized interview, ophthalmic imaging and clinical assessment. Clinical assessment included presenting and best-corrected visual acuity, refraction, slit-lamp bio-microscopy, assessment of intraocular pressure (IOP) by Goldman applanation tonometry and optic disc examination. Participants who were categorized as 'glaucoma suspect' received visual field examination (24-2 SITA static, threshold-related) and gonioscopy in addition to the standardized clinical assessment. Glaucoma was defined according to the International Society for Geographical and Epidemiological Ophthalmology classification.
Off the 5,600 names selected, 4,168 (74.4%) were eligible for the study and a total of 3,280 had attended the centralized clinic (78.7% response rate). Of these, 363 (11.07%) were categorized as 'glaucoma suspect'. There were 157 people diagnosed to have glaucoma, resulting in a crude prevalence of 4.79% and the age-standardized prevalence of 3.6% (95% confidence intervals [CI] 3.5 to 3.6). Of all the glaucoma cases, 142 (3.26%; 95% CI, 3.17 to 3.36) were primary open angle glaucoma; (POAG), 12 (0.18%; 95% CI, 0.16 to 0.20) were primary angle closure glaucoma (PACG), 2 (0.05%; 95% CI 0.03 to 0.06) were secondary glaucoma and 1 (0.06%; 95% CI 0.05 to 0.08) was congenital glaucoma. There were altogether 198 (6.04%) glaucoma suspects.
This study shows that the prevalence of glaucoma among Malays in Singapore aged 40-80 years old is 4.79% and the age-standardized prevalence is 3.6%.
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