May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Comparison of Incidence of Neovascularization Between Interrupted Suture and Continuous Suture After Penetrating Keratoplasty
Author Affiliations & Notes
  • T. Yamaguchi
    Dept. of Ophthalmology, St Lukes International Hospital, Chuo-Ku Tokyo, Japan
  • N. Ishida
    Ishida Eye Clinic, Johetsu-shi, Niigata, Japan
  • A. Yasuda
    Dept. of Ophthalmology, St Lukes International Hospital, Chuo-Ku Tokyo, Japan
  • A. Kogure
    Dept. of Ophthalmology, St Lukes International Hospital, Chuo-Ku Tokyo, Japan
  • F. M. Polack
    Ocala Eye, Ocala, Florida
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4679. doi:
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    • Get Citation

      T. Yamaguchi, N. Ishida, A. Yasuda, A. Kogure, F. M. Polack; Comparison of Incidence of Neovascularization Between Interrupted Suture and Continuous Suture After Penetrating Keratoplasty. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4679.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To compare the incidence of neovascularization between interrupted sutures (IRS) and continuous sutures (CTS) after penetrating keratoplasty (PKP).

Methods:: Twenty six eyes of 26 cases underwent PKP were analyzed. Mean age of the patients was 65 years old (46-89). Thirteen patients were male and 13 patients were female. Seventeen cases of bullous keratopathy, 5 cases of keratoconus and 2 cases of corneal dystrophy (lattice dystrophy:1, Macular dystrophy:1) were studied. Suturing Methods:8 interrupted sutures with 16 bites continuous sutures using 10-0 nylon were made. Suture knots of 8 IRS were set on the surface of host cornea and suture knot of CTS were buried host-graft junction at 12:30 position. None of the corneas had any vessels preoperatively. The number of suture with neovascularization was observed and counted using slit-lamp at the time when the vessels were most active condition from 19 to 131 days after PKP.

Results:: Average number of suture with neovascularization were 4.65 per 8 IRS and 3.65 sutures with neovascularization per 16 bites CTS. There was statistically significant difference in the rate of neovascularized sutures between IRS and CTS (p<0.01). Graft rejection was found in 2 eyes (7.7%).

Conclusions:: Interrupted suture produces vascularization at the site of the knot. This does not occur with continous suture. Suture knot stimulates the grouwth of new vessels.

Keywords: cornea: clinical science 
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