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M. Tomita, S. Shimmura, S. Inokawa, M. Kawashima, K. Tsubota, J. Shimazaki; Astigmatism Following Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4680.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate astigmatism following deep anterior lamellar keratoplasty (DALK) and to compare results with penetrating keratoplasty (PKP).
In a retrospective case control study, we investigated the medical records of post-DALK and PKP patients (host-graft size 7.5-7.75mm, 10-0 nylon single running suture) followed for more than 12 months without suture removal at Tokyo Dental College Ichikawa General Hospital, Japan. Each group had 29 eyes. We recorded the subjective astigmatism, keratometry reading, corneal topography reading (K reading, SAI, SRI), spherical equivalent, and spectacle corrected visual acuity at postoperative 3, 6, and 12 months.
Original diseases of both groups were hereditary corneal degeneration in 6 eyes, keratoconus in 6 eyes, corneal scar in 10 eyes and corneal opacity due to herpetic keratitis in 7 eyes. Subjective astigmatism at 3, 6, 12 months were -2.88, -2.68, -2.91D in the DALK group, and -2.70, -2.65, -2.88D in the PKP group. Other data at 12 months were as follows: keratometry reading was -3.56D in DALK group and -3.59D in PKP group, K reading was 44.53 in DALK group and 42.98 in PKP group, SAI was 1.51 in DALK group and 1.32 in PKP group, SRI was 1.63 in DALK group and 1.63 in PKP group, spherical equivalent was -2.42D in DALK group and -1.86D in PKP group, spectacle corrected visual acuity was 0.62 in DALK group and 0.49 in PKP group. All data were not statistically significant. 3 eyes in the PKP group experienced endothelial rejection during the follow up period.
Postoperative astigmatism was similar after DALK and PKP patients. Our data suggest that post-DALK patients achieve comparable visual function with PKP without the risk of endothelial rejection.
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