May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Impact of Contact Lens Group and Multipurpose Contact Lens Solution to Inhibit Fungal Contamination
Author Affiliations & Notes
  • T. Ide
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • D. Miller
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • E. C. Alfonso
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • T. P. O'Brien
    Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • Footnotes
    Commercial Relationships T. Ide, None; D. Miller, None; E.C. Alfonso, None; T.P. O'Brien, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4737. doi:
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    • Get Citation

      T. Ide, D. Miller, E. C. Alfonso, T. P. O'Brien; Impact of Contact Lens Group and Multipurpose Contact Lens Solution to Inhibit Fungal Contamination. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4737.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To evaluate in vitro effectiveness of CL group /multipurpose CL solution combinations to inhibit fungal contamination.

Methods:: Four different commercial soft contact lenses(group I-IV) were placed in sterile disposable contact lens cases in 2ml of either ReNu MoistureLoc(ML), ReNu MultiPlus(MP) or OPTI-FREE RepleniSH(Opti) and 0.5 McFarland of Fusarium oxysporum and incubated at 25°c. Quantitative mycologic analysis was conducted after 24,48,and72-hour incubation.

Results:: Fusarium was recovered from all 12 lens/solution combinations after 24-hours. Fungal contamination was observed for all Group II solution combinations. Growth was documented in Group I for MP and Opti and in Group III/IV for ML and MP. No Fusarium was recovered after 48 hours for any of the 12 CL group/solution combinations.

Conclusions:: The combination of contact lens group and contact lens solution may impact the effectiveness of current contact lens disinfection systems to prevent fungal contamination.

Keywords: fungal disease • contact lens • microbial pathogenesis: experimental studies 
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