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J. F. Ortega Santana, A. Pérez, E. López-Star; Visual Field Findings in Vogt-Koyanagi-Harada Syndrome. Invest. Ophthalmol. Vis. Sci. 2007;48(13):5146.
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© ARVO (1962-2015); The Authors (2016-present)
To describe visual field findings in adults with Vogt-Koyanagi-Harada Syndrome in convalescent phase.
Prospective, descriptive, cross-sectional and observational study. We included patients with diagnosis of Vogt-Koyanagi-Harada syndrome in convalescent phase, with minimum visual capacity of 20/40, without any complications. Visual field tests were done with Optoelectronic Stimulator (METROVISION®) using the program STAT94, a perimetric test, it explores 94 points in the 60 central degrees of the visual field. We divide the points of the visual field in three regions: the 15 central degrees, from 15 to 30 degrees, and from 30 to 60 degrees. Aaverage of mean deficit, corrected mean deficit, and spatial fluctuation, for each region were calculated. The mean deficit is the average visual loss that is recorded over the whole set of measuring points with respect to the normal data from age-matched controls. The corrected mean deficit provides the average sensitivity loss of the patient with respect to his or her own normal map (corrected by his own base level). Spatial fluctuation is the average of sensitivity difference between each measurement point and its neighbors, it characterizes local threshold local variations. The deficit of the three regions were recorded and compare with among them. The data were analyzed using an ANOVA test.
We included 11 patients, 10 female and 1 male (18 eyes). The mean age was 38.1 years. The average of mean deficit of all regions was 3.33 (+4.74) dB. The average of the mean deficit for each region was: 2.39 (+3.5) dB for the 15 central degrees region, 3.29 (+4.5) dB for the 15 to 30 degrees region, and 5.01 (+5.4) dB for of 30 to 60 degrees region. There was not statistical difference between the three regions. The average of the corrected mean deficit was 2.13 (+2.47) dB. The average of the spatial fluctuation was 2.35 (+1.93) dB.
We found alterations in the visual fields of patients with Vogt-Koyanagi-Harada Syndrome, specifically general and localized loss of sensitivity. We also observe greater visual field loss towards the periphery (30-60 degrees), but without a statistical significant difference.
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