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L. M. Fernandes, J. P. Paes, B. B. O. de Morais, C. M. G. da Costa, E. M. de Oliveira, F. S. Felix, T. Ono, Jr., H. Angotti, M. P. de Morais, S. T. de Queiroz; Surgical Treatment of Primary Pterygium: Comparison Between Tecniques of Autologous Conjunctive Transplant and Transplantation of Amniotic Membrane. Invest. Ophthalmol. Vis. Sci. 2007;48(13):5296.
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To determine whether the use of transplantation of amniotic membrane as surgical treatment of primary pterygium is superior in terms of recurrence aesthetic satisfaction and post surgery comfort to the conjunctival autologous conjunctive transplant.
Amniotic membrane was got from human cesarean deliveries and preserved under glycerol at 4º C for 2 months. An experimental and prospective study was done, of 228 patients (228 eyes) with primary pterygium grade 2, that underwent surgical treatment from January 2002 to October 2004. The patients had a 1 year follow-up period. 137 (60,08%) patients were male, 91 (39,92%) female and the average age was 35 (20 to 53 years old), all caucasian. two groups were chosen at random: test group (126 eyes) - amniotic membrane transplantation, control group (102 eyes) - autologous conjunctive transplant.
In the test group there were 8 reincident cases (6,3%), 102 patients (80,95%) satisfied with aesthetic and 63 (50%) related pain in the first 48 hours post operation. P.O. 17 reincident cases (16,6%) were observed in the control group, 51patients satisfied with aesthetic (50%) and 81 (81,5%) suffered pain in the 48 hours post operation P.O. The statistic analysis was done by the test of significance for equality of two proportions and all criteria showed statistic significance (z>1,96).
Amniotic membrane has been consolidated as a helpful adjunct in the treatment of infections of ocular surface. Its use is based on the capacity of benefiting the process of epithelialization. Furthermore it reduces the inflammatory processes, angiogenesis and scarring. Being a relatively simple procedure, eith low rates of reincidence and pain after surgery and high rates of aesthetic satisfaction,the transplantation of amniotic membrane reveals itself superior to autologous conjunctive transplant technique in the treatment of primary pterygium.
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