May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Enhanced Imaging of Macular Pathologies With the High Speed, Fourier Domain RTVue Optical Coherence Tomography Instrument
A. H. Rogers; R. W. Chen; J. S. Duker; C. R. Baumal; E. Reichel; I. Gorczynska; J. J. Liu; V. Srinivasan; J. S. Schuman; J. G. Fujimoto
Author Affiliations & Notes
  • A. H. Rogers
    Tufts-New England Eye Center, Boston, Massachusetts
  • R. W. Chen
    Tufts-New England Eye Center, Boston, Massachusetts
  • J. S. Duker
    Tufts-New England Eye Center, Boston, Massachusetts
  • C. R. Baumal
    Tufts-New England Eye Center, Boston, Massachusetts
  • E. Reichel
    Tufts-New England Eye Center, Boston, Massachusetts
  • I. Gorczynska
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • J. J. Liu
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • V. Srinivasan
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • J. S. Schuman
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Dept. of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
  • J. G. Fujimoto
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts
  • Footnotes
    Commercial Relationships A.H. Rogers, None; R.W. Chen, None; J.S. Duker, Optovue, Inc., F; C.R. Baumal, None; E. Reichel, None; I. Gorczynska, None; J.J. Liu, None; V. Srinivasan, None; J.S. Schuman, Optovue, Inc., F; Carl Zeiss Meditec, Inc., F; Heidelberg Engineering, F; Carl Zeiss Meditec, Inc., P; Carl Zeiss Meditec, Inc., R; Heidelberg Engineering, R; J.G. Fujimoto, Optovue, Inc., F; Carl Zeiss Meditec, Inc., P.
  • Footnotes
    Support NIH RO1-EY13178-06, RO1-EY11289-20, P30-EY08098, P30-EY13078, NSF ECS-0119452 and BES-0522845, AFOSR FA9550-040-1-0046, FA9550-040-1-0011, The Eye and Ear Fdn (Pittsburgh, PA), RPB unrestr. grant
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 5663. doi:
  • Views
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Enhanced Imaging of Macular Pathologies With the High Speed, Fourier Domain RTVue Optical Coherence Tomography Instrument
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      A. H. Rogers, R. W. Chen, J. S. Duker, C. R. Baumal, E. Reichel, I. Gorczynska, J. J. Liu, V. Srinivasan, J. S. Schuman, J. G. Fujimoto; Enhanced Imaging of Macular Pathologies With the High Speed, Fourier Domain RTVue Optical Coherence Tomography Instrument. Invest. Ophthalmol. Vis. Sci. 2007;48(13):5663.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
Abstract

Purpose:: To perform a cross-sectional study of retinal pathologies with the RTVue Fourier domain optical coherence tomography system (Optovue, Inc., Fremont, CA). To identify situations where RTVue Optical coherence tomography (OCT) provides improved performance compared to standard OCT systems.

Methods:: RTVue OCT is capable of 26,000 axial scans / second compared to 400 axial scans / second on standard time domain OCT (Stratus OCT), and ~5 µm axial resolution compared to ~10 µm resolution of standard OCT. The increased speed and resolution allows for high transverse pixel density images, dense raster scans, and three-dimensional (3D) imaging of retinal topography. High resolution RTVue OCT and standard resolution Stratus OCT were performed in the same patients, and results were correlated with standard ophthalmologic clinical exams.

Results:: RTVue OCT was performed in >75 patients with a variety of retinal pathologies, including age-related macular degeneration, diabetic retinopathy, macular edema, vitreomacular traction, macular hole, epiretinal membrane, and central serous chorioretinopathy. High resolution images captured more detail of intraretinal structures such as the photoreceptor inner segment/outer segment junction, ganglion cell layer, and retinal pigment epithelium. Pathology such as edema that could not be identified on standard OCT was identified on RTVue OCT. 3D imaging provided surgically relevant topographical and structural information in cases of macular holes and epiretinal membranes.

Conclusions:: The RTVue Fourier domain OCT instrument offers significant improvement in visualization of retinal structures compared to standard OCT. High resolution images capture details that may be missed on standard OCT. 3D imaging provides improved coverage and retinal topographical information, and it offers the potential to track pathology from visit to visit.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical • retina 
© 2007, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept