Abstract
Purpose: :
Study of corneal endothelium polymegatism changes in long time hydrogel contact lens (HCL) users when the contact lens (CL) material was changed for lotrafilcon–A.
Methods: :
Prospective study of 14 eyes with diagnosis of severe polymegatism with Bio–Optics contact specular microscopy. Coefficient of variation (CV) was used to measure corneal endothelial polymegatism. The follow up of corneal polymnegatism after the change of HCL to lotrafilcon–A (Focus Night&Day): every 3 months for 18 months; p<0,05 indicate statistic significance.
Results: :
The effect of HCL is the same for all eyes, exist different magnitude of CV endothelial behaviour when the material of CL was changed for lotrafilcon–A (p=0,0001) and significant tendency to decrease during the time (p<0,0001, angle coeficient –0,00817 and confidence limits 95%: –0,012006 to –0,00434).
Conclusions: :
The lotrafilcon–A may decrease severe corneal polymegatism secondary long time HCL users.
Keywords: cornea: endothelium • contact lens • imaging/image analysis: clinical