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C.S. Bouchard, A.Z. Ahmad, W.C. Park, B. Hayek, S. Blatt; The Role of Platelet Count in Decision–Making for Suspected Giant Cell Arteritis . Invest. Ophthalmol. Vis. Sci. 2006;47(13):785.
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© ARVO (1962-2015); The Authors (2016-present)
To study the role of platelet count in the clinical work–up of giant cell arteritis (GCA), as suggested by a recently published model.
The is a retrospective case review analysis. Patient data will be limited from 1995–2005, with final diagnosis confirmed by temporal artery biopsy. Patient laboratory data, in particular platelet count, will be applied to the "computer–based decision analytic model" and "pretest probability set" identified in the Niederkohr et al study: "Management of the Patient with Suspected Temporal Arteritis." (Ophthalmology. Vol 112, No 5, May 2005).
Thrombocytosis has been a more potent indicator of excluding GCA. Of 27 cases, only 6 (22.2%) patients with suspected GCA demonstrated thrombocytosis. 2 of these 6 (33.3%, or 7.41% of total) patients carried a final diagnosis of GCA, based on temporal artery biopsy. On the other hand, 17 (63.0%) of the 27 patients without thrombocytosis did not have GCA.
Our preliminary data supports a portion of Niederkohr et al’s model. Platelet count is most effective in its absence; lack of thrombocytosis is associated with the exclusion of GCA.
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