Abstract
Purpose: :
To investigate the correlation between retinal sensitivity measured with micro perimeter (MP–1) and retinal thickness with optical coherence tomography (OCT) in eyes with diabetic macular edema (DME).
Methods: :
A prospective study was done in 33 eyes of 26 patients with DME. The age of the patients of ranged from 51 to 76 (mean 58.8 ± 11.8 years). Foveal retinal thickness ranged from 239 to 927 µm (mean 517 ± 142 µm). We classified the type of DME into 3 types: retinal swelling type (16 eyes), cystoid macular edema type (9 eyes) and serous retinal detachment type (8 eyes). OCT was performed with the Fast Macular Thickness Map protocol (six 6 mm radial line scans). The data were analyzed with Retinal Map program, which divided the macular area with 6 mm diameter into 9 fields, and we obtained the mean retinal thickness in each field. Retinal sensitivities were measured with MP–1(stimulus duration: 200msec, threshold strategy: 4–2–1). We used a new stimulus pattern with 37 stimulating points (Goldmann III size) corresponding to each field of Retinal Map program.
Results: :
The mean retinal sensitivity was significantly correlated with the mean retinal thickness in retinal swelling type (r = 0.49, P < 0.0001; y = 544.5–12.1x) and cystoid macular edema type (r = 0.70, P < 0.0001; y = 698.6–26.1x), however, no correlation in serous retinal detachment type (r = 0.11, P = 0.37; y = 599.6–4.0x).
Conclusions: :
In eyes with DME, retinal sensitivity is correlated with retinal thickness in retinal swelling type and cystoid macular edema type in 9 fields of Retinal Map program of OCT. Especially in eyes with cystoid macular edema type, there is a strong correlation between retinal sensitivity and retinal thickness.
Keywords: diabetic retinopathy