May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Treatment of Keratectasia After LASIK With Riboflavin/UV Light Cross–Linking
Author Affiliations & Notes
  • A.U. Koeller
    Dept of Ophthalmology, University of Dresden, Dresden, Germany
  • M. Kohlhaas
    Dept of Ophthalmology, University of Dresden, Dresden, Germany
  • E. Spoerl
    Dept of Ophthalmology, University of Dresden, Dresden, Germany
  • L. Pillunat
    Dept of Ophthalmology, University of Dresden, Dresden, Germany
  • Footnotes
    Commercial Relationships  A.U. Koeller, None; M. Kohlhaas, None; E. Spoerl, None; L. Pillunat, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 1317. doi:
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      A.U. Koeller, M. Kohlhaas, E. Spoerl, L. Pillunat; Treatment of Keratectasia After LASIK With Riboflavin/UV Light Cross–Linking . Invest. Ophthalmol. Vis. Sci. 2006;47(13):1317.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Keratectasia after LASIK is a rare but severe complication. Penetrating keratoplasty is the common way of treatment to stabilize or improve visual function. We report about a new technique of molecular cross linking of corneal stroma to avoid progression of the disease.

Methods: : We treated 16 eyes of 16 patients with keratectasia after myopic LASIK. The presurgical refraction was –3 – –6.5 D and the corneal thickness before LASIK was > 530 µm in 15 of the patients, just one had a corneal thickness of < 500 µm. All patients were treated with riboflavin/UV light (370 nm, 30 min) cross linking. Visual acuity, corneal pachymetry and corneal curvature were measured before and after the treatment. The follow up time was 3 – 36 months.

Results: : In the first weeks after cross linking visual function was reduced (–0.5 snellen lines +/– 1 snellen line) but after 3 months the patients showed an improvement of vision by 1.4 +/– 1 snellen lines. The corneal thickness showed no significant change after treatment (mean value 525 µm). During the follow up time of one year the astigmatism values remained stable (mean: 4.5 +/– 2D). In all of the patients a progression of keratectasia could be avoided by the cross linking technique.

Conclusions: : To avoid keratectasia after LASIK the guidelines of the committee for refractive surgery must be respected. After LASIK a long term follow up is necessary because keratectasia can develop slowly but also very rapidly. Riboflavin/UV light cross linking is a new technique which stops progression of keratectasia by stiffening the anterior part of the corneal stroma.

Keywords: keratoconus • refractive surgery: complications • refractive surgery: corneal topography 
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