May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Photodynamic Therapy With Verteporfin For Corneal Neovascularization
Author Affiliations & Notes
  • M. Galantuomo
    Ophthalmology, University, Cagliari, Italy
  • E. Peiretti
    Ophthalmology, University, Cagliari, Italy
  • I. Zucca
    Ophthalmology, University, Cagliari, Italy
  • M. Fossarello
    Ophthalmology, University, Cagliari, Italy
  • Footnotes
    Commercial Relationships  M. Galantuomo, None; E. Peiretti, None; I. Zucca, None; M. Fossarello, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 1629. doi:
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    • Get Citation

      M. Galantuomo, E. Peiretti, I. Zucca, M. Fossarello; Photodynamic Therapy With Verteporfin For Corneal Neovascularization . Invest. Ophthalmol. Vis. Sci. 2006;47(13):1629.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To describe the effect of photodynamic therapy (PDT) using verteporfin (Visudyne ®) on corneal neovascularization (CNV) in twenty patients.

Methods: : Twenty patients with corneal neovascularization were treated with a non–thermal laser light at 689 nm delivered fifteen minutes after an intravenous infusion of verteporfin. Postoperative outcome of neovascularization was followed clinically (inflammation, intraocular pressure and visual acuity) and photographically (colour photographs and corneal fluorescein and indocyanine green (ICG) angiography) for a minimum of one year.

Results: : Successful photothrombosis of corneal neovasculararization was obtained immediately after treatment in all patients, and regression was verified by corneal fluorescein and ICG angiography. In 12 patients partial vessel recanalization was observed after one month, and treatment was repeated, with complete regression of new vessel. No relevant side effects were observed in our cases.

Conclusions: : PDT with verteporfin is an effective and safe procedure indicated for patients with corneal neovascularization: howerver, multiple sessions may be required.

Keywords: photodynamic therapy • cornea: clinical science • laser 
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