Abstract
Purpose: :
To analyze the morphological changes of the macula following full macular translocation (FMT) with 360 degree retinotomy in patients with neovascular age–related macular degeneration (AMD).
Methods: :
Twenty–five eyes of 25 consecutive patients with subfoveal predominantly classic choroidal neovascularization who underwent FMT between August 2001 and March 2004 were analyzed prospectively. Seven patients were excluded from the study because of missed visits and incomplete data. In addition to the complete ophthalmological examination, color fundus photographs, fluorescein angiography and optical coherence tomography (OCT) were performed at baseline and at 3,6 and 12 months, postoperatively. Primary outcomes were foveal thickness and foveal configuration. Macular edema, intraretinal cyst, neurosensorial retinal detachment and foveal atrophy were also noted.
Results: :
Eighteen patients (12 male, 6 female), aged between 67 – 91 years (mean 80.3 years) were analyzed. OCT examination at the baseline examination showed serous detachment of neurosensory epithelium in 9 eyes. The normal pattern of foveal depression was not seen in any patient. Mean retinal thickness at the fovea before FMT was 648.27+/–177.95 µM (mean +/– SD). Foveal thickness measurements at 3,6 and 12 Months after surgery were 188.80+/–48.61 µM, 226,86+/–92,11µM and 275,89+/–117,65µM, respectively. OCT showed a normal concave foveal configuration in 10 (55.5%) of 18 eyes at the month 12 examination. Macular edema, foveal atrophy and intraretinal cyst were detected in 6 (33.3%), 2 (11.1%) and 4 (22.2%) of 18 eyes, respectively. No neurosensory retinal detachment was observed during the follow–up.
Conclusions: :
The presented study showed the restoration of macular morphology after FMT in patients with neovascular AMD. Optical coherence tomography is a precise method for detecting and analyzing the changes of macular morphology following macular surgery.
Keywords: age-related macular degeneration • vitreoretinal surgery • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)