Abstract
Purpose: :
To evaluate the location of polypoidal vessels in polypoidal choroidal vasculopathy (PCV) in Japanese patients.
Methods: :
We retrospectively reviewed medical records of 100 eyes of 92 patients (66 men, 26 women; mean 68.3 years) diagnosed with PCV, and analyzed the location of polypoidal vessels based on indocyanine green angiograms. We measured the distance and angle between the center of the optic disc/fovea and polypoidal vessels in each case, converted the location of polypoidal vessels into X–Y coordinates, and depicted them graphically. We also evaluated the location of polypoidal vessel in relation to the distance from the center of the disc/fovea, the size of the greatest linear dimension of the total lesion (reddish–orange lesion, serous/hemorrhagic detachment of retinal pigment epithelium, thick contiguous blood, or atrophic scarring), and previous fundus lesion treatment such as photocoagulation and radiation.
Results: :
Polypoidal vessels were predominantly located in the macula than in the peripapillary lesion (p<0.01). Polypoidal vessels in cases with a treatment history were located more distantly from the macula than those without treatment (p=0.043). Polypoidal vessels with larger polypoidal lesion (>4 disc diameters) were located further from the fovea than those with smaller polypoidal lesion (p<0.01).
Conclusions: :
The location of polypoidal vessels in PCV in Japanese patients is mainly seen in the macula, and the treatment history and the total lesion size may be associated with the location of the polypoidal vessel.
Keywords: age-related macular degeneration • retina • macula/fovea