Abstract
Purpose: :
To demonstrate the standardized reproducibility of lesion base dimensions in extra macular nevi using the Optos® P200 imaging system which utilizes scanning laser ophthalmoscope technology to effectively capture ultra–wide field, high–resolution images (2000 x 2000 pixels). Current literature supports the concept that photographic documentation of nevi that may have malignant potential is useful for objective assessment of tumor growth.
Methods: :
Five patients with choroidal tumors were imaged with the Optos®P200. Comparisons was made to standard 50 o fundus photography with respect to the lesion size in disc diameters. With the Optos system, the optic nerve can be seen along with the entire nevus in most cases, whereas with standard imaging,, using a 50 degree Topcon digital fundus camera or equivalent, a composite is usually needed for large lesions which may introduce errors.
Results: :
For the five cases, we found that the lesion extent in disk diameters along the largest dimension was +/– 0.25 to 0.30 for those done with the Optos technique versus +/– 0.50 to 0.60 for nevi imaged conventionally. The differences between these mean dimensions were not significant (low power to show differences) however as we expand the sample size such differences may prove noteworthy. In all of the patients the interpretation of the dimensions of the nevi had a high degree of correlation amongst three masked observers. The color saturation of the tumor was more evident in the standard pictures. Measurement of the disc diameters of the lesion was facilitated in Optos®.
Conclusions: :
In patients with clinically suspicious extra macular Optos® fundus imaging has the advantage of simplicity in that it usually can show the entire lesion as well as the nerve head. In convention imaging, the nerve head is often not depicted in the lesion images.
Keywords: choroid • tumors • imaging/image analysis: clinical