May 2006
Volume 47, Issue 13
ARVO Annual Meeting Abstract  |   May 2006
Change in Myopia Over Three Years Among Wearers of Continuous Wear Silicone Hydrogel Lenses and Daily Wear Hydrogel Contact Lenses
Author Affiliations & Notes
  • B. Long
    North America MMCC, CIBA Vision Corp, Duluth, GA
  • P. Bergenske
    College of Optometry, Pacific University, Forest Grove, WA
  • R.L. Chalmers
    Clinical Trial Consultant, Atlanta, GA
  • S.M. Dillehay
    North America MMCC, CIBA Vision Corp, Duluth, GA
  • J.T. Barr
    College of Optometry, The Ohio State University, Columbus, OH
  • P. Donshik
    Health Center, University of Connecticut, Bloomfield, CT
  • G. Secor
    Private Practice, Huntington Beach, CA
  • J. Yoakum
    Groate Eyecare Associates, Greensboro, NC
  • Footnotes
    Commercial Relationships  B. Long, CIBA Vision Corp., E; P. Bergenske, Cooper Vision, F; CIBA Vision, C; R.L. Chalmers, CIBA Vision Corp, C; CIBA Vision Corp., R; S.M. Dillehay, CIBA Vision Corp., E; J.T. Barr, CIBA Vision Corp., C; P. Donshik, CIBA Vision Corp., C; G. Secor, CIBA Vision Corp., C; J. Yoakum, CIBA Vision Corp., C.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 2384. doi:
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      B. Long, P. Bergenske, R.L. Chalmers, S.M. Dillehay, J.T. Barr, P. Donshik, G. Secor, J. Yoakum; Change in Myopia Over Three Years Among Wearers of Continuous Wear Silicone Hydrogel Lenses and Daily Wear Hydrogel Contact Lenses . Invest. Ophthalmol. Vis. Sci. 2006;47(13):2384.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : Earlier studies with continuous wear (CW) of silicone hydrogel lenses showed that users had a lower rate of myopic progression compared to subjects who wore hydrogel lenses on a 6 night extended wear (EW) schedule. The purpose of this study was to compare the long term results for lotrafilcon A CW lens wear compared to hydrogel daily wear (DW).

Methods: : Subjects were enrolled in a 3–year non–randomized trial in which investigators could choose to place a subject in CW with lotrafilcon A lenses or 2 weekly replacement DW with hydrogel lenses. An age matched subset was randomly selected from among the CW and DW subjects who completed the study. Baseline and 3 year spectacle subjective refractive errors were compared to test whether there was a significant difference in the change in refractive error over time.

Results: : 36 CW subjects aged 27.9 + 12.4 years had baseline refractive error of –3.59 + 1.99 DS. The 36 DW subjects were aged 27.9 + 12.5 years and had baseline refractive error of –2.10 + 1.78 DS (p<0.01). CW subjects increased in myopia by 0.03 DS while DW subjects increased in myopia by 0.40 DS (p=0.007). There was no significant change in corneal curvature by keratometry for the CW subjects and there was slight but significant increase in the steepness of the steep K reading for the DW subjects (p<0.05). The proportion of CW subjects with presenting VA of 20/20 or better remained relatively stable, varying from 80 to 86% during the study, while the proportion for DW subjects ranged from 63% to 78% at follow–up visits through 36 months in the study.

Conclusions: : Subjects with higher refractive errors were placed in the CW group by investigators in this study. Notwithstanding, there was a larger amount of myopic progression among the age matched users of DW hydrogel lens wearers that caused a portion of them to present with under–correction during scheduled annual visits. CW silicone hydrogel lenses maintained a more stable refractive error over the 3 year observation period in this study.

Keywords: accessory optic system/pretectum 

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