Abstract
Purpose: :
To report foveolitis as a new manifestation of dengue fever
Methods: :
Retrospective case series. Clinical records of patients with dengue fever and ocular manifestations were reviewed. The clinical findings, optical coherence tomography, fundus fluorescein, indocyanine green angiography, electroretinography findings and clinical progress are reported.
Results: :
11 eyes of 7 patients presented with acute visual loss 5 to 7 days after classic dengue fever, associated with an orange spot at the fovea. Optical coherence tomography showed a corresponding outer neurosensory retinal and retinal pigment epithelial thickening. 2 cases of the dengue fever–associated foveolitis were each associated with branch retinal vein occlusion and branch retinal artery. They were treated with immunosuppressives including systemic steroids, immunoglobulins with improvement in visual acuity and corresponding resolution shown on optical coherence tomography.
Conclusions: :
Dengue fever can cause foveolitis with severe acute visual loss. OCT can be used to diagnose and monitor progression of dengue fever–associated foveolitis.
Keywords: uveitis-clinical/animal model • macula/fovea • imaging/image analysis: clinical