May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Combined Tenotomy + Anderson Procedure for Treatment of Acquired Vertical Nystagmus and Infantile Horizontal Nystagmus Associated With Diplopia and Oscillopsia
Author Affiliations & Notes
  • R.L. Tomsak
    Daroff–Dell'Osso Ocular Motility Laboratory, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, OH
    Neurology,
    Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH
  • Z. Wang
    Daroff–Dell'Osso Ocular Motility Laboratory, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, OH
    Biomedical Engineering,
    Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH
  • L.F. Dell'Osso
    Daroff–Dell'Osso Ocular Motility Laboratory, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, OH
    Neurology and Biomedical Engineering,
    Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH
  • J.B. Jacobs
    Daroff–Dell'Osso Ocular Motility Laboratory, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, OH
    Neurology,
    Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH
  • Footnotes
    Commercial Relationships  R.L. Tomsak, None; Z. Wang, None; L.F. Dell'Osso, None; J.B. Jacobs, None.
  • Footnotes
    Support  DVA Merit Review
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 2512. doi:
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      R.L. Tomsak, Z. Wang, L.F. Dell'Osso, J.B. Jacobs; Combined Tenotomy + Anderson Procedure for Treatment of Acquired Vertical Nystagmus and Infantile Horizontal Nystagmus Associated With Diplopia and Oscillopsia . Invest. Ophthalmol. Vis. Sci. 2006;47(13):2512.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To investigate the effects of combined Tenotomy + Anderson procedure on both acquired vertical (downbeat) nystagmus (DBN) and horizontal infantile nystagmus (IN). Tenotomy improved visual acuity and reduced oscillopsia in patients with IN and acquired pendular nystagmus. Its effectiveness combined with other surgeries should also be accessed.

Methods: : Patient 1 had DBN, oscillopsia, strabismus, and diplopia; he adopted a chin–down (upgaze) position. Asymmetric superior rectus recessions and inferior rectus tenotomies reduced right hypertropia and rotated both eyes downward. Patient 2 had horizontal IN, a 20º left–eye exotropia, and alternating fixation (left eye in left gaze, right eye in right gaze). Eight mm lateral rectus recessions and medial rectus tenotomies were performed. Horizontal and vertical eye movements were recorded pre– and post–surgically using high–speed digital video. The expanded nystagmus acuity function (NAFX), peak–to–peak amplitudes, and frequencies were measured.

Results: : Patient 1: The NAFX peak was moved from 10º up to primary position; primary–position NAFX values were improved by 17%. Visual acuity increased 20% from 20/25 to 20/20+1. Vertical NAFX values increased across the –10º to +5º vertical range. Right hypertropia was reduced to 3–4º, foveation time per cycle increased from 88 ms to 178ms (102%), vertical–component amplitude was reduced by 46%, and frequency was unchanged at ∼3 Hz. Diplopia and oscillopsia were decreased. Patient 2: The procedure transformed two lateral, narrow NAFX vs. gaze angle curves (due to fixating–eye changes) into one broad curve with a 81.3% increase in primary position where acuity increased from 20/150 to 20/80, with a slight decrement in left–gaze. Diplopia decreased, the ability to converge was regained, and to hold gaze, improved. Right hypertropia was reduced, foveation time per cycle increased from 35.5 ms to 126.9 ms (257.4%), horizontal–component amplitude was reduced by 45.7%, and frequency remained unchanged at ∼4 Hz.

Conclusions: : Increased NAFX values and visual acuities plus reduced diplopia and oscillopsia demonstrated the effectiveness of combined Tenotomy + Anderson procedure in DBN and IN. Tenotomy should be part of the treatment plan for selected cases of acquired and infantile nystagmus.

Keywords: nystagmus • strabismus • eye movements 
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