Ultra–High Speed and Three–Dimensional Imaging of Anterior Eye Segments by Swept–Source OCT

Abstract

 

Purpose:

 

To demonstrate high–speed structural sectionalimaging and three–dimensional tomography of the anterioreye segments by Swept–Source OCT (SS–OCT).

 

Methods:

 

A prototype of 1.3 micron wavelength swept–sourceOCT was developed to examine anterior eye segments. The SS–OCTis capable of 40 B–scans/sec at 500 axial scans/image.Three–dimensional volume tomography contains 200 x 200line–scans/volume is acquired by 2 second.

 

Results:

 

In vivo OCT of the anterior eye chamber of a healthyvolunteer was acquired. High–sensitivity (113 dB) B–scanimage shows anatomic features of the AC, such as cornea, sclera,iris including iris pigment epithelium, scleral spur, and trabecularmesh work. High–speed movies (40 frames per sec) revealdynamic motion of the AC, such as a constriction process oran accommodation process. Volume tomography shows the three–dimensionalanatomic structure of the AC, e.g., the cornea, iris, scleraor so on.

 

Conclusions:

 

High–speed SS–OCT will allow investigationof kinetic process of the AC, and comprehensive screening ofthe entire structure of the AC. Volume OCT helps to survey theentire three–dimensional features AC. Fig. 1: Three–dimensionally reconstructed corneal topography.The three–dimensional data, not only surface topographybut also volume tomography, was acquired in two seconds. Thistopographic image is reconstructed from the three–dimensionalvolume data. Fig. 2: Three–dimensional tomography of in vivo humanAC. Anatomic features are evident. 

 

 

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • anterior segment • motion-2D