May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Retinal Birefringence Measurement With Polarization Sensitive Fourier Domain Optical Coherence Tomography
M. Yamanari; Y. Yasuno; S. Makita; Y. Hong; Y. Nakamura; V.D. Madjarova; M. Itoh; T. Yatagai
Author Affiliations & Notes
  • M. Yamanari
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • Y. Yasuno
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • S. Makita
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • Y. Hong
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • Y. Nakamura
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • V.D. Madjarova
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • M. Itoh
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • T. Yatagai
    Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
  • Footnotes
    Commercial Relationships  M. Yamanari, None; Y. Yasuno, None; S. Makita, None; Y. Hong, None; Y. Nakamura, None; V.D. Madjarova, None; M. Itoh, None; T. Yatagai, None.
  • Footnotes
    Support  Japan Science and Technology agency, Development of Systems and Technology for Advanced Measurement and Analysis; KAKENHI: 15760026
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 3309. doi:
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      M. Yamanari, Y. Yasuno, S. Makita, Y. Hong, Y. Nakamura, V.D. Madjarova, M. Itoh, T. Yatagai; Retinal Birefringence Measurement With Polarization Sensitive Fourier Domain Optical Coherence Tomography . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3309.

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Abstract

Purpose: : To demonstrate the depth resolved birefringence imaging of retina using polarization sensitive Fourier domain optical coherence tomography system.

Methods: : Fiber–based polarization sensitive Fourier domain optical coherence tomography system was developed. Fiber birefringence was compensated with surface reflection from the retina. Phase retardation and orientation of the birefringence can be measured with Jones matrix based algorism in addition to conventional cross sectional OCT. Synchronized two line–CCD cameras allow high–speed measurement of birefringence of retina in vivo.

Results: : Retinal phase retardation map was visualized as depth–resolved image. Retinal birefringence tomograph of healthy volunteers were analyzed and compared to earlier literatures; the results of polarization sensitive time domain optical coherence tomography and histological knowledge.

Conclusions: : Polarization sensitive Fourier domain optical coherence tomography allowed visualizing depth–resolved image of retinal birefringence. Fiber–based system facilitates clinical application when the system is implemented to fundus camera or slit–lamp microscope. High speed, high sensitive measurement and accurate knowledge of the retinal birefringence are important to evaluate retina for clinicians.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina 
© 2006, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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