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M. Yamanari, Y. Yasuno, S. Makita, Y. Hong, Y. Nakamura, V.D. Madjarova, M. Itoh, T. Yatagai; Retinal Birefringence Measurement With Polarization Sensitive Fourier Domain Optical Coherence Tomography . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3309.
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© ARVO (1962-2015); The Authors (2016-present)
To demonstrate the depth resolved birefringence imaging of retina using polarization sensitive Fourier domain optical coherence tomography system.
Fiber–based polarization sensitive Fourier domain optical coherence tomography system was developed. Fiber birefringence was compensated with surface reflection from the retina. Phase retardation and orientation of the birefringence can be measured with Jones matrix based algorism in addition to conventional cross sectional OCT. Synchronized two line–CCD cameras allow high–speed measurement of birefringence of retina in vivo.
Retinal phase retardation map was visualized as depth–resolved image. Retinal birefringence tomograph of healthy volunteers were analyzed and compared to earlier literatures; the results of polarization sensitive time domain optical coherence tomography and histological knowledge.
Polarization sensitive Fourier domain optical coherence tomography allowed visualizing depth–resolved image of retinal birefringence. Fiber–based system facilitates clinical application when the system is implemented to fundus camera or slit–lamp microscope. High speed, high sensitive measurement and accurate knowledge of the retinal birefringence are important to evaluate retina for clinicians.
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