May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Reproducibility of Macular Thickness Measurements Using High Speed, Ultrahigh Resolution Optical Coherence Tomography (Spectral OCT, SOCT)
Author Affiliations & Notes
  • K. Sung
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • H. Ishikawa
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • G. Wollstein
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • L. Kagemann
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • R.A. Bilonick
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • M. Wojtkowski
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA
  • J.S. Duker
    New England Eye Center, Tufts–New England Medical Center, Boston, MA
  • V. Srinivasan
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA
  • J.G. Fujimoto
    Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA
  • J.S. Schuman
    UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • Footnotes
    Commercial Relationships  K. Sung, None; H. Ishikawa, None; G. Wollstein, None; L. Kagemann, None; R.A. Bilonick, None; M. Wojtkowski, None; J.S. Duker, None; V. Srinivasan, None; J.G. Fujimoto, Carl Zeiss Meditec, Inc., P; J.S. Schuman, Carl Zeiss Meditec, Inc., C; Carl Zeiss Meditec, Inc., P.
  • Footnotes
    Support  NIH Grants RO1–EY013178–6, RO1–EY11289–20, and P30–EY008098, NSF ECS–0119452, AFOSR FA9550–040–1–0046, Research to Prevent Blindness and The Eye and Ear Foundation (Pittsburgh)
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 3371. doi:
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    • Get Citation

      K. Sung, H. Ishikawa, G. Wollstein, L. Kagemann, R.A. Bilonick, M. Wojtkowski, J.S. Duker, V. Srinivasan, J.G. Fujimoto, J.S. Schuman; Reproducibility of Macular Thickness Measurements Using High Speed, Ultrahigh Resolution Optical Coherence Tomography (Spectral OCT, SOCT) . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3371.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To compare the reproducibility of macular thickness measurements using Stratus OCT and state–of–the–art high speed, ultrahigh resolution OCT (spectral OCT, SOCT).

 
Methods:
 

One randomly chosen eye of fifteen healthy subjects was scanned 3 times per day in 3 visits by single operator with Stratus OCT and SOCT. A Stratus OCT fast macular scan (6 radial scans, each with 128 A–scans) and a SOCT radial scan (24 radial scans, each with 1483 A–scans) were acquired. Intrasubject–intravisit and intrasubject–intervisit coefficient of variance (COV) and intraclass correlation coefficient (ICC) of overall macular thickness were computed for Stratus OCT and the 2 sets of SOCT data; comparing all 24 SOCT linear scans and using only 6 SOCT linear scans which corresponds to the Stratus OCT location.

 
Results:
 

Overall macular thickness reproducibility data are listed in the Table.  

 
Conclusions:
 

The SOCT demonstrated reproducible intra and intervisit measurements of macular thickness.

 
Keywords: imaging/image analysis: clinical • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • image processing 
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