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T. Ban, K. Ishida, K. Kawase, T. Yamamoto; Comparison Of Three Different Methods For Longitudinal Evaluation Of Visual Fields . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3393.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate mean deviation slope for longitudinal evaluation of visual fields and compare it with those of the Advanced Glaucoma Intervention Study (AGIS) or Collaborative Intervention Glaucoma Treatment Study (CIGTS) methods
A total of 169 eyes (90 patients) with primary open–angle glaucoma or normal–tension glaucoma were followed for 10 years and examined with program 30–2 of the Humphrey Field Analyzer (Humphrey Instruments, San Leandro, CA) at 6 –months. The average of mean deviation (MD) at baseline was –8.08+/–6.65dB. The methods used by AGIS and CIGTS were applied to all patients and compared with MD slopes calculated using an Humphrey Field Analyzer statistical software, Hfa Files version 5 ( Beeline, Tokyo, Japan) . Main Outcome Measurement: MD slope, Change of AGIS score (ΔAGIS) and CIGTS score (ΔCIGTS), correlation coefficient, concordance in detecting progressive or stable visual fields (VFs)
The average MD slope was –0.23 +/–0.37 dB/year for 10 years. ΔAGIS and ΔCIGTS were 2.15 +/–3.84 and 2.18 +/–4.13 for 10 years, respectively. Significant correlation was observed among 3 methods (R2=0.57–0.54, P<0.01). The rate of VF progression was 30.2%, 29.0%, and 28.4% by MD slope, AGIS, and CIGTS criteria, respectively. Concordance in detecting progressive or stable VFs was 79.3%, 77.6%, and 84.0% between MD slope and AGIS criteria, MD slope and CIGTS method, and AGIS and CIGTS criteria, respectively.
MD slope detects progression or stability in a similar proportion of eyes compared with AGIS and CIGTS methods.
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