Purchase this article with an account.
R.J. George, H. Arvind, M. Baskaran, P.G. Paul, P. Raju, S.V. Ramesh, G. Kumaramanickavel, C. McCarty, L. Vijaya; Risk Factors for Glaucoma in a Rural South Indian Population . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3429.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To identify the risk factors for glaucoma in an adult rural South Indian population.
Three thousand nine hundred and twenty four of 4800 enumerated participants aged 40 years and above from a population based glaucoma prevalence study were included. All subjects underwent a comprehensive ophthalmic examination including vision testing, refraction, Goldman applanation tonometry, central corneal thickness measurements, 4 mirror gonioscopy, LOCS II lens grading, dilated fundus examination, strereobiomicroscopic disc examination, optic disc photography, Frequency Doubling Perimetry (FDP) Screening C– 20 –1 and FDP Full threshold N –30, Humphrey Visual fields SITA Standard 30–2 were performed for diagnosis. The International Society for Geographical and Epidemiologic Ophthalmology (ISGEO) criteria were used to diagnose glaucoma (Foster et al. Br J Ophthalmol. 2002 Feb;86(2):238–42). The association between demographic and clinical parameters, literacy, occupation, weighted score on C–20–1 (Patel et al Am J Ophthalmol. 2000 Mar;129(3):323–7) and mean deviation on Full threshold FDP, on the diagnosis of glaucoma were studied.
Hundred and sixty subjects (5.47%) were diagnosed to have glaucoma of any etiology. Increasing age [Odds ratio:1.08 (95% CI: 1.06,10.9)] was significantly (p<0.0001) associated with glaucoma. After adjusting for age and gender increasing intraocular pressure [OR1.24 (95% CI: 1.20–1.28)], aphakia [OR 2.19 (95% CI: 1.34 –3.58)], pseudophakia [OR 3.86 (95% CI: 2.45–6.08)], increasing FDP score on C 20–1[OR 1.05 (95% CI: 1.03–1.06)] and increasing mean deviation on Full threshold FDP [OR1.13 (95% CI: 1.06–1.21)] were significantly associated with the diagnosis of glaucoma.
Increasing age and aphakia or pseudophakia were associated with increased risk of disease. FDP parameters on both screening and full threshold were associated with disease.
This PDF is available to Subscribers Only