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F.M. Heussen, S. Joeres, B. Prinz, H. Llacer, N. Fawzy, B. Kirchhof, A.M. Joussen; Quality of Life Findings in Patients With Peripheral Autologous Translocation of the Choroid . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3488.
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© ARVO (1962-2015); The Authors (2016-present)
To present findings from quality of life questionnaires, given to patients that showed unilateral or bilateral age related macular degeneration (AMD) and underwent PATCH–surgery on one eye.
The patients were interviewed before PATCH and at 6 and 12 months after enrolment using the National Eye Institute Visual Function Questionnaire–German Translation (NEI–VFQ). Included into the study were eyes with all subtypes of AMD and visual acuity of 0.4 to 1.4 (logMAR). Subgroups of unilateral (n= 3) and bilateral (n=26) cases were formed, based on visual acuity. Patients were considered for the bilateral group, if the fellow eye had an initial acuity of >0.5 (logMAR).
The overall NEI–VFQ scores dropped by a mean of 5.21 points in the bilateral group and by 10.84 points in the unilateral group at the 6 month follow–up respectively. The subscale that was affected the most was Dependency (–21 points) for bilateral cases. Nevertheless, the subscale general vision remained stable (±0 points). The NEI–VFQ scores in the unilateral (48.33) group exceeded the ones in the bilateral (43.15) by 5.18 points in average. Mean VFQ–score increased from 6 to 12 months follow–up (mean increase 7.09 ± 11, n=9, min –7.00 / max +28). In both groups there was no correlation found between visual acuity in the study eye and corresponding NEI–VFQ scores.
Patients with bilateral AMD presented an overall loss of subjective quality of life after PATCH–surgery. Data also suggests that visual acuity after PATCH–surgery does not correlate with VFQ scores neither in unilateral nor in bilateral cases. The lack of correlation between functional outcome and subjective quality of life findings indicate that different means of determining the expected patient benefits are needed. The available data is still limited to a 1 year follow–up and needs to be expanded for a decisive interpretation.
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