May 2006
Volume 47, Issue 13
ARVO Annual Meeting Abstract  |   May 2006
One–Year Results After Combined Phacoemulsification and Deep Lamellar Endothelial Keratoplasty (Phaco/DLEK)
Author Affiliations & Notes
  • S. Pramanik
    Ophthalmology, University of Iowa, Iowa City, IA
  • C.C. Robinson
    Ophthalmology, University of Iowa, Iowa City, IA
  • J.E. Sutphin
    Ophthalmology, University of Iowa, Iowa City, IA
  • K.M. Goins
    Ophthalmology, University of Iowa, Iowa City, IA
  • Footnotes
    Commercial Relationships  S. Pramanik, None; C.C. Robinson, None; J.E. Sutphin, None; K.M. Goins, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 3609. doi:
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      S. Pramanik, C.C. Robinson, J.E. Sutphin, K.M. Goins; One–Year Results After Combined Phacoemulsification and Deep Lamellar Endothelial Keratoplasty (Phaco/DLEK) . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3609.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To report best spectacle corrected visual acuity (BSCVA) results one year after combined Phaco/DLEK for cataract and Fuchs dystrophy. Secondary outcomes include postoperative spherical equivalent, endothelial cell counts, keratometric astigmatism, and wavefront aberrations.

Methods: : A retrospective, consecutive review was performed of patients with visually significant cataract and Fuchs dystrophy who underwent combined Phaco/DLEK at the University of Iowa and had at least 12 months of postoperative follow–up. Baseline data included age, BSCVA, preoperative keratometric astigmatism, wavefront aberrations, target refraction, and donor endothelial cell counts. Outcome measures were recorded 1, 3, 6, and 12 months postoperatively.

Results: : Among the 12 eyes of 12 patients, the mean age at surgery was 70.58(+/–8.34)years. Preoperatively, the mean BSCVA was 20/70 (range 20/30–20/250), mean keratometric astigmatism was 1.55(+/–1.61) diopters (D) , mean total wavefront aberration (RMS) was 3.27(+/–4.57) µm, mean lower order aberration (LOA) was 2.40(+/–3.11) µm and mean higher order aberration (HOA) was 1.92(+/–3.41) µm. The mean target spherical equivalent was –0.62(+/–0.75) D and the mean baseline donor endothelial cell density was 3067(+/–389) c/mm2. One year postoperatively, the mean BSCVA was 20/40 (range 20/20–20/100), mean spherical equivalent was 0.25(+/–1.47) D, mean keratometric astigmatism was 1.19 (+/–0.72) D, mean RMS was 1.13(+/–0.69) µm, mean LOA was 0.82(+/–0.41) µm , and mean HOA was 0.62(+/–0.7) µm. Endothelial cell counts at one year were 2235(+/–410) c/mm2 .

Conclusions: : Combined Phaco/DLEK offers good visual rehabilitation for patients with Fuchs and cataract. It results in minimal keratometric astigmatism and reduced wavefront aberration with acceptable endothelial levels one year after surgery.

Keywords: clinical (human) or epidemiologic studies: outcomes/complications • cornea: clinical science • transplantation 

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