May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Automated Lamellar Therapeutic Keraoplasty for Stromal Opacities and Anterior Dystrophies
Author Affiliations & Notes
  • J. Rooij
    Cornea, Eye Hospital Rotterdam, Rotterdam, The Netherlands
  • H.V. Cleijnenbreugel
    Cornea, Eye Hospital Rotterdam, Rotterdam, The Netherlands
  • A.J. M. Geerards
    Cornea, Eye Hospital Rotterdam, Rotterdam, The Netherlands
  • I.V. D. Meulen
    Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands
  • L. Remeijer
    Cornea, Eye Hospital Rotterdam, Rotterdam, The Netherlands
  • Footnotes
    Commercial Relationships  J. Rooij, None; H.V. Cleijnenbreugel, None; A.J.M. Geerards, None; I.V.D. Meulen, None; L. Remeijer, None.
  • Footnotes
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Investigative Ophthalmology & Visual Science May 2006, Vol.47, 3618. doi:
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      J. Rooij, H.V. Cleijnenbreugel, A.J. M. Geerards, I.V. D. Meulen, L. Remeijer; Automated Lamellar Therapeutic Keraoplasty for Stromal Opacities and Anterior Dystrophies . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3618.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : to describe anatomical, refractive and visual outcome after microkeratome assisted anterior lamellar keratoplasty. Comparison of the results with a group of 21 eyes after deep anterior lamellar keratoplasty (DALK).

Methods: : Six eyes were operated with the aid of the Carriazo–Barraquer (CB) microkeratome using baseplate depths ranging from 130 – 300 µm. Donor tissue was prepared with the Moria artificial anterior chamber and the CB microkeratome with baseplate depths from 200 – 350 µm. Patients were followed up at 1 week, 1, 3 and 6 months. Flap thickness was measured at 3 months with a confocal microscope.

Results: : Flap thickness was 116% (105 – 127%) of the baseplate depth used. Average best spectacle corrected visual acuity (BSCVA) was 0.35 (0.2 – 0.5; SD 0.11) after 1 month and 0.53 (0.3 –0.7; SD 0.2) after 3 months. Spherical equivalent was +0.9 (–1 – +1.75; SD 1.3) before surgery and +1.8 (–0.75 – + 3.5; SD 1.9) at 3 months. Average K was 41 (36.8 – 44.5; SD 3.5) before– and 42 (40.25 – 44; SD 1.7) at 3m postoperatively. Average astigmatism was 1D (0 – 2D; SD 0.7) at 1m and 2.1D (1 – 3; SD 0.9) at 3m. In 2 patients with opacities in the residual bed, hard contact lens VA was 0.4 and 0.25. In the DALK group, BSCVA after an average FU of 35 (12 – 61) months was 0.33 (0.1 – 0.7; SD 0.18).

Conclusions: : BSCVA recovery is faster and astigmatism lower than after PK. BSCVA results are better than after DALK, probably due to a smoother interface and/or less irregular astigmatism. Opacities left in the residual bed reduced VA more than irregular astigmatism.

Keywords: cornea: clinical science • clinical (human) or epidemiologic studies: outcomes/complications 
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