Correlations Between Optic Nerve Head Parameters by OCT and Visual Field Findings With SAP, FDT SWAP and Flicker Perimetry

Abstract

Purpose: : Correlations Between Optic Nerve Head Parameters by OCT and Visual Field Findings With SAP, FDT SWAP and Flicker Perimetry

Methods: : Subjects were 42 eyes of 42 patients with OAG and glaucoma suspects, and 40 eyes of 40 normal subjects. The patients with OAG and glaucoma suspects were tested by HFA 24–2 full threshold (SAP), SITA SWAP, FDT Matrix (24–2–5, 24–2–1) and flicker perimetry (4–zone 38S) using Octopus 311. The visual fields were evaluated by the mean deviation (MD) of SAP and the number of abnormal points in the SAP, FDT, SWAP and flicker field data. The ONH parameters were measured by Stratus OCT. The correlation between the functional changes in the visual fields and structural changes in the ONH parameters was investigated.

Results: : Significant differences were observed between the normal and glaucoma groups (including glaucoma suspects) in all the ONH parameters. The ONH parameters, especially the cup–to–disc vertical ratio, correlated significantly with the MD of SAP and the number of abnormal points in the SAP, FDT, SWAP and flicker field. However, in the early stage of OAG (MD > –6dB) and glaucoma suspects, a significant correlation was only found between the ONH parameters and MD of SAP. Moreover, significant correlations were also seen between the ONH parameters and RNFL thickness in the glaucoma group but not in the groups of the early stage of OAG and glaucoma suspects.

Conclusions: : The analysis of ONH with OCT is a useful method for detecting glaucoma. However, there is less correlation between the structural changes of ONH parameters and the functional changes of the visual field evaluated by FDT, SWAP and flicker perimetry in the early stage of OAG and glaucoma suspects.

Keywords: optic disc • visual fields