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J.G. Sanchez, R.A. Garcia, L. Wu, Z. Piskulich, J.F. Arevalo; Optical Coherence Tomography Characteristics of Group 2A Idiopathic Parafoveal Telangiectasis Stage 2 to 5 . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4021.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the optical coherence tomography (OCT) characteristics of patients with group 2A idiopathic parafoveal telangiectasis (IPFT), and to correlate them with biomicroscopy and fluorescein angiography (FA) findings based on Gass and Blodi’s staging classification for group 2A IPFT.
Twenty eyes of 10 consecutive patients with IPFT underwent biomicroscopic fundus examination, color fundus photography, fluorescein angiography, and OCT. Main outcome measures were OCT characteristics, and correlation with biomicroscopy and FA.
The most common findings to differentiate between stages 2 through 5 of group 2A IPFT seen on OCT were: 1) The presence of hyporeflective intraretinal spaces in the absence of retinal thickening (15/20; 75%), and highly reflective dots in the retina (13/20; 65%) in stage 2; 2) An area of outer, and inner retina with similar high reflectivity (13/20; 65%), and high reflectivity with evidence of disruption and/or thickening at the retinal pigment epithelium (RPE)/choriocapillaris complex (11/20; 55%) in stage 3, 3) A high reflective area nasal or temporal to the fovea in the inner or outer retinal layers (6/20; 30%) in stage 4 suggesting RPE proliferation and migration; and 4) A fussiform thickening, and duplication of the highly reflective RPE/choriocapillaris complex corresponding to choroidal neovascularization (1/20; 5%) in stage 5. Our OCT characteristics correlated well with biomicroscopic and FA findings for stage 4 and 5. However, the hyporeflective spaces that are evident on OCT in stage 2 could not be seen clinically at the slit lamp or on FA. In addition, our OCT findings on eyes with group 2A IPFT stage 3 have not been previously described.
Optical coherence tomography findings in group 2A IPFT were characteristic for each stage, and may be helpful in making the diagnosis as well as defining the anatomical staging proposed by Gass and Blodi. Optical coherence tomography complements biomicroscopic, and FA findings in the evaluation of group 2A IPFT.
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