May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Characteristics Of Cataract In Eyes With Long Axial Length In A Chinese Population
Author Affiliations & Notes
  • Y. Yamashiro
    Division of Vision Research for Environmental Health, Institute of Kanazawa Medical University, Uchinada, Japan
  • J. Qu
    Division of Vision Research for Environmental Health, Institute of Kanazawa Medical University, Uchinada, Japan
  • J. Tao
    Division of Vision Research for Environmental Health, Institute of Kanazawa Medical University, Uchinada, Japan
  • Y. Kawakami
    Department of Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • M. Kojima
    Division of Vision Research for Environmental Health, Institute of Kanazawa Medical University, Uchinada, Japan
    Department of Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • R. Honda
    Department of Social and Environmental Medicine,
    Kanazawa Medical University, Uchinada, Japan
  • H. Sasaki
    Department of Ophthalmology,
    Kanazawa Medical University, Uchinada, Japan
  • K. Sasaki
    Division of Vision Research for Environmental Health, Institute of Kanazawa Medical University, Uchinada, Japan
  • Footnotes
    Commercial Relationships  Y. Yamashiro, None; J. Qu, None; J. Tao, None; Y. Kawakami, None; M. Kojima, None; R. Honda, None; H. Sasaki, None; K. Sasaki, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 4142. doi:
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      Y. Yamashiro, J. Qu, J. Tao, Y. Kawakami, M. Kojima, R. Honda, H. Sasaki, K. Sasaki; Characteristics Of Cataract In Eyes With Long Axial Length In A Chinese Population . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4142.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To describe the relationship between axial length and cataract and examine morphologic characteristics of high myopia in Chinese.

Methods: : Subjects comprised 583 participants aged > 40 yrs (mean: 58.3±9.6 yrs.) of an ophthalmic examination in Liaoning Province China between July and September 2004. Changes in the crystalline lens were photographed using an Anterior Eye Segment Analysis System (EAS–1000, NIDEK) under maximal pupillary dilation and examined. Classification of nuclear, cortical, cortical opacity within a 3mm diameter of the pupil (CEN) and posterior subcapsular cataract (PSC) were determined from the photographed images by a single observer using the WHO system. Lens thickness and anterior chamber depth were obtained with an A–scan ultrasound device. Axial length was measured and eyes assigned to 4 groups; group A (<mean length), group B (23mm to 26mm), group C (26mm to 29mm) and group D (>26mm). Statistical analysis was performed using logistic regression, controlling for age and sex.

Results: : The mean axial length was 23.1±1.7mm. Prevalences of nuclear, cortical and PSC in group D were significantly higher than in the other three groups at 24.1%, 48.3% and 17.4%, respectively. Cortical cataract and PSC grade 2 and over in groups C and D were significantly higher than those in groups A and B. Increased risk of the three main types of cataract at grade 1 and over was seen in group D compared with group A with odds ratios of 5.5 (95% CI 2.2–11.3) in cortical, 6.3 (95% CI 2.5–15.7) in CEN, 2.7 (95% CI 1.0–7.4) in nuclear and 5.7 (95% CI 1.8–18.1) in PSC. Asteroid opacity along the posterior Y–suture was seen in eyes with long axis (group B and C). The rate of asteroid opacity in PSC in groups A, B, C and D was 0, 0, 50 and 80%, respectively.

Conclusions: : Prevalence in the three main types of cataract was significantly high in long axis eyes. PSC in eyes with long axial length showed a asteroid opacity along the posterior Y–suture.

Keywords: cataract • myopia • clinical (human) or epidemiologic studies: risk factor assessment 
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