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G. Manni, F. Oddone, M. Centofanti, M. Sampalmieri, G. Cupo, D. Gazzaniga, M. Parravano, L. Tanga; Influence Of High Myopia On Central Corneal Thickness . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4453.
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to evaluate the relation between CCT and biometric, tonometric and demographic charactersistics in highly myopic eyes.
inclusion criteria were: age greater than 18 years, fully ability to understand and sign an informed consent, refractive error ranging from +1.50 to –35 diopters. Exclusion criteria were: previous ocular surgery, systemic pathologies possibly affecting CCT, any ocular diseases different from myopia. Patients performed a complete ophthalmological examination including axial lenght (AL) measurement, cheratometry, ultrasound pachymetry and Goldmann applanation tonometry. The relation between CCT and demographic, biometric, and tonometric data was explored by linear regression analysis.
Fiftyeight subjects with refractive error ranging from +1.50 to –33 diopters were enrolled in this study (mean age 65.74 ± 13.64 years). CCT seemed not to be related to any of the variables considered in this study (AL: r2 0.009, p=0.49, spherical equivalent: r2 0.035, p=0.16, age: r2 0.002, p=0.72, mean corneal curvature: r2 0.061, p=0.06. A statistically significant relation between AL and intraocular pressure has been found (r2=0.19 p=0.001).
CCT has been found not to be related to either demographic or biometric characterstic in highly myopic subjects. Intraocular pressure has been found to be weakly lineary related to axial length.
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