Abstract
Purpose: :
To assess the effect of cyclopentolate 1% on the intraocular pressure (IOP) in a paediatric population.
Methods: :
Twenty children (40 eyes) 5 to 13 years of age (mean 7.7 ± 2.3) were studied. Patients with narrow angle and known or suspected glaucoma were excluded from the study. Subjects’ refraction ranged between –15 and +4.5 D (mean –1.25 ± 5.8 D). The IOP was measured with Goldmann aplanation and with non–contact tonometer before and after administration of the cyclopentolate (one drop, two times at ten minute interval).
Results: :
After cycloplegia, IOP remained the same in 13 cases, increased in 9 eyes (but stayed inferior to 20 mmHg) and decreased in 18 eyes. Mean IOP by aplanation before and after cycloplegia was respectively 12.75 ± 3.1 and 11.8 ± 3.2 (P=0.02) and with non–contact tonometer respectively 14.5 ± 3.3 and 13.7 ± 3.3 (P=0.08). IOP measured with non–contact tonometer was significantly higher than IOP measured with Goldmann aplanation (P<0.05).
Conclusions: :
Cyclopentolate 1%, widely used in children, doesn’t seem to increase IOP. This study confirms that values of IOP in children are higher with the non–contact tonometer.
Keywords: intraocular pressure • drug toxicity/drug effects • infant vision