May 2006
Volume 47, Issue 13
ARVO Annual Meeting Abstract  |   May 2006
Comparison Between Two Protocols of Macular Imaging by Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy
Author Affiliations & Notes
  • N. Duchateau
    Ophthalmology, Cochin, Paris, France
  • L. Haddad
    Ophthalmology, Cochin, Paris, France
  • D. Monnet
    Ophthalmology, Cochin, Paris, France
  • E. Delaire
    Ophthalmology, Cochin, Paris, France
  • C. Elie
    Ophthalmology, Cochin, Paris, France
  • R.D. Levinson
    Ocular Inflammatory Disease Center, Jules Stein Eye Institute, David Geffen School of Medicine, UCLA, Los Angeles, CA
  • A.P. Brézin
    Ophthalmology, Cochin, Paris, France
  • Footnotes
    Commercial Relationships  N. Duchateau, None; L. Haddad, None; D. Monnet, None; E. Delaire, None; C. Elie, None; R.D. Levinson, None; A.P. Brézin, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 4504. doi:
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      N. Duchateau, L. Haddad, D. Monnet, E. Delaire, C. Elie, R.D. Levinson, A.P. Brézin; Comparison Between Two Protocols of Macular Imaging by Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4504.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To compare results obtained with the Fast Imaging protocol with results from Standard Macular Imaging by Optical Coherence Tomography (OCT) in patients with Birdshot chorioretinopathy.

Methods: : Eighty patients with Birdshot chorioretinopathy, seen in a single center, were included. Optical Coherence Tomography was performed with an OCT3 (OCT3 Zeiss–Humphrey, San Leandro, CA, USA). Two protocols of acquisition were used: Macular Thickness Map (MTM) and Fast Macular Thickness Map (FMTM). MTM was based on consecutive acquisitions of 6 sections with 512 A–scans and FMTM was based on simultaneous acquisitions of 6 sections with 128 A–scans. Intraclass correlation coefficients were calculated for macular thickness in 1 mm diameter (A1), foveal thickness and macular volume. The duration of both examination methods was timed during a repeat visit visit for a subgroup of 40 patients.

Results: : The mean duration of acquisition was 65.6 seconds with the MTM protocol and 9.6 seconds with the FMTM protocol. Measurements by MTM and FMTM were respectively 187 ± 98.5 µm (range 85–768) and 197 ± 114.7 µm (range 84–826) for average foveal thickness, 224 ± 87.3 µm (range 118–768) and 228.5 ± 104 µm (range 118–804) for average macular thickness (A1), and 7.1 ± 1.4 mm3 (range 4.6– 14.7) and 7,0 ± 1.6 mm3 (range 4.2–15.3) for average macular volume. The intraclass correlation coefficient was 0.98 [95% CI 0.95–0.99] for macular thickness, 0.97 [95% 0.94–0.99] for foveolar thickness and 0.92 [95% CI 0.95–0.99] for macular volume. The mean of the differences between standard and fast protocol was –3.8 µm for foveal thickness (paired t–test, p=0.008) and –10.6µm for macular thickness (p<0.001). No statistical difference was observed for macular volume.

Conclusions: : Results from Fast and Standard macular imaging by OCT were highly correlated, but with slightly greater measurements of macular thickness using Fast macular imaging.

Keywords: autoimmune disease • retinochoroiditis • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 

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