The Histogenesis, Clinical Features And Histopathological Analysis On 83 Cases Of Ciliary Body Neoplasms

Abstract

Purpose: : By analyzing the histogenesis and classification, histopathologic characteristics, clinical feature and the key point of differential diagnosis of ciliary body neoplasms, the study provided the basis for clinical diagnosis and treatment.

Methods: : Eighty–three specimens of ciliary body neoplasms on file (1959∼2005) were analyzed and studied for the characteristics of location, histogenesis, clinical presentation and histopathology.

Results: : Of the 83 specimens, 59 tumors were located in the ciliary body (71.1%), and 24 lesions involved the iris or choroid (28.9%). Benign neoplasms (59.0%) were more than malignant ones (41.0%). According to the results of histogenetic classification, pigmented tumors (42 cases) were ranked in the first place. 24 cases were malignant melanoma, occupied 28.9% of the ciliary body neoplasms and 57.1% of the pigmented tumors; 18 cases were melanocytoma, occupied 21.7% of the ciliary body neoplasms and 42.9% of the pigmented tumors. Followed by neuroepithelial and neurogenic tumors, 30 cases (36.2%) include 6 of granulomatous lesions (7.2%) and 2 of epithelioid leiomyoma (2.4%). Other three unusual tumors were of 1 case respectively (3.6%).

Conclusions: : The study found that the pigmented neoplasms were ranked in the first place of ciliary body tumors, in which melanoma of ciliary body were majority. By further recognizing the clinical features and histopathologic characteristics of ciliary body neoplasms, it may help clinical ophthalmologists to make correct diagnosis and proper treatment.

Keywords: ciliary body • tumors • pathology: human